Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.76 |
| ▸ | F3 | P13726 | 1/20 | 0.76 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500068 | 0.87 | F7 (0.61) | F7F3KDM4EHPGDHSD17B10 | |
| SCHEMBL30071319 | 0.87 | F7 (0.61) | F7F3KDM4EHPGDHSD17B10 | |
| SCHEMBL3700465 | 0.87 | KDM4E (0.66) | F7F3SMAD3KDM4EHPGD | |
| SCHEMBL22777743 | 0.87 | KDM4E (0.66) | F7F3SMAD3KDM4EHPGD | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL720582 | 0.86 | F7 (1.00) | F7F3SMAD3KDM4EHPGD | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL6921825 | 0.85 | F7 (0.96) | F7F3SMAD3KDM4EHPGD | |
| SCHEMBL20494483 | 0.84 | KDM4E (0.76) | F7F3SMAD3KDM4EHPGD | |
| SCHEMBL1550144 | 0.83 | MMP2 (0.65) | F7F3SMAD3KDM4EHPGD | |
| SCHEMBL6478522 | 0.82 | SMAD3 (0.60) | F7F3SMAD3KDM4EHPGD | |
| SCHEMBL3501101 | 0.80 | KDM4E (0.56) | F7F3KDM4EALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | F7 4709/4885F3 4737/4885SMAD3 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.