Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634605 | 0.77 | CYP1A2 (0.44) | TDP1ALOX15ALDH1A1MAPTKMT2A | |
| SCHEMBL15059660 | 0.75 | PARP1 (0.44) | TDP1L3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL12447848 | 0.74 | ALOX15 (0.40) | TDP1ALOX15L3MBTL1ALDH1A1LMNA | |
| SCHEMBL7541755 | 0.74 | TDP1 (0.40) | TDP1ALOX15ALDH1A1LMNAKMT2A | |
| SCHEMBL29501815 | 0.73 | ALOX15 (0.43) | TDP1ALOX15ALDH1A1MAPTKMT2A | |
| SCHEMBL1518035 | 0.73 | ALOX15 (0.43) | TDP1ALOX15ALDH1A1MAPTKMT2A | |
| SCHEMBL4960375 | 0.73 | ALOX15 (0.43) | TDP1ALOX15ALDH1A1MAPK1CHEK1 | |
| SCHEMBL4959186 | 0.73 | ALOX15 (0.43) | TDP1ALOX15ALDH1A1LMNANPSR1 | |
| SCHEMBL9166710 | 0.73 | CA12 (0.47) | TDP1ALOX15L3MBTL1ALDH1A1LMNA | |
| SCHEMBL1025152 | 0.73 | NQO1 (0.44) | TDP1ALOX15L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | PTMS, IK, PHAX | TDP1 1447/4885ALOX15 4871/4885L3MBTL1 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.