Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501658 | 0.94 | FFAR1 (0.41) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL13312055 | 0.81 | RXRG (0.52) | FFAR1FFAR4CYP4F2CYP4A11RXRA | |
| SCHEMBL13312631 | 0.81 | FFAR1 (0.45) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL13312651 | 0.78 | FFAR1 (0.40) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL3503712 | 0.78 | RXRA (0.56) | FFAR1FFAR4ALDH1A1GAARXRA | |
| SCHEMBL13311850 | 0.77 | PARP1 (0.40) | ALDH1A1GAACYP4F2CYP4A11HDAC6 | |
| SCHEMBL13312714 | 0.77 | FFAR1 (0.41) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL13312652 | 0.77 | PTGER4 (0.41) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL13312656 | 0.77 | FFAR1 (0.44) | FFAR1FFAR4ALDH1A1GAACYP4F2 | |
| SCHEMBL3503170 | 0.76 | PPARG (0.47) | FFAR1FFAR4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| CN-101553469-A | Carboxylic acid derivatives | ASTELLAS PHARMA INC (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | FFAR1 14/4885FFAR4 15/4885ALDH1A1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.