Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312589 | 0.88 | FFAR1 (0.38) | FFAR1FFAR4ALDH1A1GAAPKM | |
| SCHEMBL13311844 | 0.86 | ALDH1A1 (0.38) | ALDH1A1GAAPKMAVPR2RXRG | |
| SCHEMBL13312807 | 0.85 | FFAR1 (0.39) | FFAR1FFAR4ALDH1A1GAAPKM | |
| SCHEMBL13312592 | 0.84 | NOTUM (0.39) | FFAR1FFAR4ALDH1A1GAAPKM | |
| SCHEMBL13312050 | 0.83 | ALDH1A1 (0.35) | ALDH1A1GAAPKMAVPR2RXRG | |
| SCHEMBL13312663 | 0.83 | FFAR1 (0.46) | FFAR1FFAR4ALDH1A1GAAPKM | |
| SCHEMBL13312716 | 0.82 | FFAR1 (0.42) | FFAR1FFAR4ALDH1A1GAAMRGPRX4 | |
| SCHEMBL13312664 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4ALDH1A1GAAMRGPRX4 | |
| SCHEMBL13312665 | 0.80 | FFAR1 (0.49) | FFAR1FFAR4ALDH1A1GAAMRGPRX4 | |
| SCHEMBL13312072 | 0.77 | RXRG (0.46) | FFAR1FFAR4RXRGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | FFAR1 14/4885FFAR4 15/4885ALDH1A1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.