Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049817 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2POLBTDP1CASP6CTDSP1 | |
| SCHEMBL3909822 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBKDM4EMAPTMAPK1 | |
| SCHEMBL16241294 | 0.79 | POLB (0.58) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL18198899 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBTDP1CASP6CTDSP1 | |
| SCHEMBL985487 | 0.73 | RORA (0.47) | SMN1; SMN2POLBTDP1CASP6TRPV4 | |
| SCHEMBL761217 | 0.72 | ALDH1A1 (0.63) | SMN1; SMN2POLBTDP1CASP6CTDSP1 | |
| SCHEMBL4309721 | 0.72 | RORA (0.46) | SMN1; SMN2POLBTDP1CASP6TRPV4 | |
| SCHEMBL19456661 | 0.71 | MAPT (0.38) | SMN1; SMN2POLBTDP1CASP6CTDSP1 | |
| SCHEMBL22734676 | 0.71 | ALDH1A1 (0.37) | POLBTDP1CASP6CTDSP1KDM4E | |
| Trimethylammonium SCHEMBL22734536 | 0.71 | MAPT (0.38) | POLBTDP1CASP6CTDSP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649311-B2 | Temperature-sensitive fluorescent probe for introduction into cell | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2023-05-16 | — | — | US | disclosed |
| US-11199537-B2 | Temperature-sensitive fluorescent probe for introduction into cell | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2021-12-14 | — | — | US | disclosed |
| US-20190128874-A1 | TEMPERATURE-SENSITIVE FLUORESCENT PROBE FOR INTRODUCTION INTO CELL | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2019-05-02 | — | — | US | disclosed |
| US-20190113505-A1 | TEMPERATURE-SENSITIVE FLUORESCENT PROBE FOR INTRODUCTION INTO CELL | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2019-04-18 | — | — | US | disclosed |
| US-10191035-B2 | Temperature-sensitive fluorescent probe for introduction into cell | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20140342390-A1 | TEMPERATURE-SENSITIVE FLUORESCENT PROBE FOR INTRODUCTION INTO CELL | THE UNIVERSITY OF TOKYO (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | GSTO1, GSTP1, GSR | SMN1; SMN2 4672/4885POLB 2753/4885TDP1 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.