Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM6A | O15550 | 1/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642938 | 0.88 | PSMD14 (0.68) | KDM4EPSMD14MAP2K1SLC40A1KDM4A | |
| SCHEMBL30744938 | 0.83 | KDM4E (1.00) | KDM4EPSMD14MAP2K1ALOX12KDM4A | |
| SCHEMBL6018142 | 0.83 | KDM4E (0.73) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL6068105 | 0.83 | KDM4E (1.00) | KDM4EPSMD14MAP2K1ALOX12KDM4A | |
| SCHEMBL6068217 | 0.82 | KDM4E (0.68) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL17113034 | 0.82 | KDM4E (0.71) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL20952065 | 0.82 | KDM4E (0.77) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL13709235 | 0.82 | KDM4E (0.71) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL15758767 | 0.82 | KDM4E (0.71) | KDM4EPSMD14MAP2K1PDE4APDE4B | |
| SCHEMBL3899127 | 0.81 | KDM4E (0.68) | KDM4EPSMD14TDP1CYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| CN-101553469-A | Carboxylic acid derivatives | ASTELLAS PHARMA INC (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | KDM4E 2414/4885PSMD14 3040/4885MAP2K1 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.