Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL5317575 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL1130092 | 1.00 | — | — | |
| Imidazole SCHEMBL27893028 | 0.97 | — | — | |
| Imidazole SCHEMBL27941696 | 0.97 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28178838 | 0.97 | — | — | |
| Imidazole SCHEMBL5333604 | 0.97 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL1445454 | 0.97 | — | — | |
| Imidazole SCHEMBL28412052 | 0.97 | — | — | |
| Imidazole SCHEMBL29154119 | 0.97 | — | — | |
| Imidazole SCHEMBL897 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678542-B2 | Charge tags and the separation of nucleic acid molecules | THIRD WAVE TECHNOLOGIES, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090078574-A1 | CHARGE TAGS AND THE SEPARATION OF NUCLEIC ACID MOLECULES | THIRD WAVE TECHNOLOGIES, INC. (US) | 2009-03-26 | — | — | US | disclosed |
| EP-1385996-B1 | Charge tag and separation of nucleic acid molecules | THIRD WAVE TECH INC (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7384746-B2 | Charge tags and the separation of nucleic acid molecules | THIRD WAVE TECHNOLOGIES, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| EP-0904275-B1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | UNIV MCGILL (CA) | 2006-05-17 | — | — | EP | disclosed |
| EP-1112281-B1 | PTERIDINE NUCLEOTIDE ANALOGS | US GOV HEALTH & HUMAN SERV (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20050130179-A1 | Charge tags and the separation of nucleic acid molecules | THIRD WAVE TECHNOLOGIES, INC. (US) | 2005-06-16 | — | — | US | disclosed |
| US-6861518-B2 | Hybrid oligonucleotide | MCGILL UNIVERSITY (CA) | 2005-03-01 | — | — | US | disclosed |
| US-6780982-B2 | COMPOSITION FOR USE AS DETECTION AND SEPARATION TOOLS IN NUCLEOTIDE SEQUENCES ANALYSIS | THIRD WAVE TECHNOLOGIES, INC. | 2004-08-24 | — | — | US | disclosed |
| US-20040097722-A9 | Preparation of phosphorothioate oligomers | MCGILL UNIVERSITY | 2004-05-20 | — | — | US | disclosed |
| WO-2000000499-A1 | METHOD FOR PREPARING OLIGONUCLEOTIDES WITH BORANOPHOSPHATE LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-06 | — | — | WO | disclosed |
| US-5945521-A | Preparation of phosphorothioate oligomers | MCGILL UNIVERSITY (CA) | 1999-08-31 | — | — | US | disclosed |
| EP-0904275-A1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | McGILL UNIVERSITY (CA) | 1999-03-31 | — | — | EP | disclosed |
| EP-0759927-B1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | US GOV HEALTH & HUMAN SERV (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5734041-A | Preparation of chiral phosphorothioate oligomers | MCGILL UNIVERSITY (CA) | 1998-03-31 | — | — | US | disclosed |
| WO-1997014710-A1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | MCGILL UNIVERSITY (US) | 1997-04-24 | — | — | WO | disclosed |
| US-5612468-A | GENETIC ENGINEERING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0759927-A1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5525711-A | MONOMERS FOR DNA AMPLIFICATION PROCEDURES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995031469-A1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130179-A1 | Charge tags and the separation of nucleic acid molecules | NSUN2, NSUN3, NCL | ALDH1A1 3799/4885FKBP5 2620/4885 |
| US-20090078574-A1 | CHARGE TAGS AND THE SEPARATION OF NUCLEIC ACID MOLECULES | NSUN2, NSUN3, NCL | ALDH1A1 3799/4885FKBP5 2620/4885 |
| US-20040097722-A9 | Preparation of phosphorothioate oligomers | RNGTT, NUDT1, OSGEP | ALDH1A1 3421/4885FKBP5 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.