Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667174 | 0.82 | LMNA (0.39) | BLMTRPA1 | |
| SCHEMBL1052619 | 0.82 | LMNA (0.39) | BLMTRPA1 | |
| Trifluoroacetic Acid SCHEMBL720969 | 0.81 | ACE2 (0.46) | BLMACE2 | |
| Trifluoroacetic Acid SCHEMBL3918426 | 0.80 | ACE2 (0.53) | MLYCDACE2 | |
| SCHEMBL11429360 | 0.78 | LMNA (0.36) | BLMTRPA1 | |
| Trifluoroacetic Acid SCHEMBL12497790 | 0.77 | ACE2 (0.42) | DPP8DPP7ACE2 | |
| Trifluoroacetic Acid SCHEMBL349303 | 0.77 | KDM4C (0.39) | BLMATRACE2 | |
| SCHEMBL1657981 | 0.75 | LMNA (0.43) | BLMACE2TRPA1 | |
| SCHEMBL16832065 | 0.75 | BLM (0.39) | BLMRNPEPSLC7A5ACE2 | |
| SCHEMBL1657739 | 0.73 | LMNA (0.42) | BLMACE2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647882-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-8268631-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20090229352-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | BLM 3624/4885ATR 1234/4885GRN 4582/4885 |
| US-20090229352-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | BLM 3624/4885ATR 1234/4885GRN 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.