SCHEMBL350447

SCHEMBL350447

COc1cc(N2C(=O)C=CC2=O)cc(N2C(=O)C=CC2=O)c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.70
FAAH O00519 3/20 0.56
G6PD P11413 2/20 0.55
TLR9 Q9NR96 1/20 0.55
HSP90AA1 P07900 4/20 0.54
CCR6 P51684 2/20 0.54
NSD2 O96028 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
GSK3A P49840 1/20 0.44
GSK3B P49841 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11350785 0.96 MGLL (0.70) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL19067074 0.88 MGLL (0.61) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL136617 0.83 MGLL (1.00) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL29827199 0.82 MGLL (1.00) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL136584 0.82 MGLL (1.00) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL28071934 0.81 MGLL (0.96) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL8641616 0.81 MGLL (0.70) MGLLFAAHG6PDHSP90AA1CCR6
SCHEMBL28454152 0.78 MGLL (0.89) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL29310161 0.76 MGLL (0.65) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL26605015 0.75 MGLL (0.63) MGLLFAAHG6PDTLR9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3729517-A1 PHOTOVOLTAIC ROADWAY ASSEMBLY Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO (NL) 2020-10-28 EP claimed
US-20200336098-A1 PHOTOVOLTAIC ROADWAY ASSEMBLY NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2020-10-22 US claimed
EP-3503213-A1 PHOTOVOLTAIC ROADWAY ASSEMBLY Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2019-06-26 EP claimed
US-5300585-A Having improved cure reversion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-04-05 US claimed
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent SIKA TECHNOLOGY AG (CH) 2026-02-17 US disclosed
US-11987730-B2 Waterbased one coat adhesive composition DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2024-05-21 US disclosed
US-20240006183-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING AMIDE SOLVENT NISSAN CHEMICAL CORPORATION (JP) 2024-01-04 US disclosed
US-11798810-B2 Resist underlayer film-forming composition containing amide solvent NISSAN CHEMICAL CORPORATION (JP) 2023-10-24 US disclosed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
US-20220372238-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2022-11-24 US disclosed
EP-4039733-A1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN Arkema, Inc. (US) 2022-08-10 EP disclosed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 EP disclosed
EP-0191931-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 EP disclosed
EP-0345825-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-13 EP disclosed
US-4803250-A AROMATIC CARBOXYLIC ANHYDRIDE, BISMALEIMIDE, SULFUR, ACCELERATOR, NONREVERTING, ANTICRACKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-02-07 US disclosed
EP-0191931-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-27 EP disclosed
US-4085164-A MOLDING MATERIALS, ADHESIVES, LAMINATES, COATINGS RHONE-POULENC INDUSTRIES (FR) 1978-04-18 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed
US-3978152-A HEAT-RESISTANT RESINS DERIVED FROM A BIS-IMIDE, AN EPOXY RESIN AND A POLYAMINE RHONE-POULENC INDUSTRIES (FR) 1976-08-31 US disclosed
US-3966531-A Compositions containing silanes possessing imide groups RHONE-POULENC INDUSTRIES (FR) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent CA1, CA3, CA12 MGLL 2570/4885FAAH 462/4885G6PD 3979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.