Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281465 | 0.86 | GSTP1 (0.62) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL3511031 | 0.79 | TXNRD1 (0.53) | MAPTKMT2AHTTMAPK1NPC1 | |
| SCHEMBL29405540 | 0.78 | MAPT (0.71) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL137897 | 0.78 | MAPT (0.71) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL13236138 | 0.77 | MAPT (0.60) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL10752315 | 0.77 | MAPT (0.63) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL11366224 | 0.76 | MAPT (0.69) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL13355661 | 0.74 | MAPT (0.66) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL24118868 | 0.72 | KMT2A (0.57) | MAPTLMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL11649358 | 0.72 | FBP1 (0.61) | MAPTLMNAKMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | claimed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | claimed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | claimed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | GSTO1, GSTP1, GSR | MAPT 3504/4885LMNA 4722/4885KMT2A 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.