SCHEMBL3513133

SCHEMBL3513133

NC(=O)n1c(S)nc2cc(S(=O)(=O)O)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 4/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CASP6 P55212 1/20 0.35
CNR2 P34972 6/20 0.34
NPC1 O15118 1/20 0.34
CNR1 P21554 1/20 0.33
PTGER4 P35408 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
APEX1 P27695 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TSHR P16473 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24672647 0.78 CA12 (0.47) CA12CA1CA2CA9ALDH1A1
SCHEMBL824443 0.70 ALDH1A1 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL824451 0.66 HDAC6 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL824422 0.66 HDAC6 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL21713276 0.65 HDAC6 (0.47) CA12CA1CA2ALDH1A1HSD17B10
SCHEMBL29593464 0.65 HDAC6 (0.47) CA12CA1CA2ALDH1A1HSD17B10
SCHEMBL8380244 0.65 ALDH1A1 (0.36) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL6269792 0.63 PKM (0.50) ALDH1A1HSD17B10TSHRTDP1NT5E
SCHEMBL5922114 0.63 PKM (0.50) ALDH1A1HSD17B10TSHRTDP1NT5E
SCHEMBL4750976 0.62 CASP3 (0.40) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086177-A1 METHOD FOR PREPARING A LITHOGRAPHIC PRINTING PLACE PRECURSOR Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-3086176-A1 A LITHOGRAPHIC PRINTING METHOD Fujifilm Corporation (JP) 2016-10-26 EP disclosed
US-7858291-B2 imagewise exposure, protective layer comprises water-soluble polyvinyl alcohol; phosphonium salts FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-20060194150-A1 imagewise exposure, protective layer comprises water-soluble polyvinyl alcohol; phosphonium salts FUJI PHOTO FILM CO., LTD. 2006-08-31 US disclosed
EP-1696268-A2 Lithographic printing plate precursor, method for preparation of lithographic printing plate precursor, and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2006-08-30 EP disclosed