Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516030 | 0.88 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL3510332 | 0.87 | RECQL (0.40) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL4872665 | 0.79 | — | — | |
| SCHEMBL4871261 | 0.74 | SMN1; SMN2 (0.37) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL3516033 | 0.73 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL4872675 | 0.72 | — | — | |
| SCHEMBL4871262 | 0.70 | MEN1 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL27615261 | 0.70 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL7238580 | 0.69 | MAPT (0.43) | SMN1; SMN2ALDH1A1MDM4LMNAMAPT | |
| SCHEMBL7238575 | 0.69 | MAPT (0.43) | SMN1; SMN2ALDH1A1MDM4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110318290-A1 | Compounds and Methods for Inhibiting Axillary Malodour | GIVAUDAN SA (CH) | 2011-12-29 | — | — | US | disclosed |
| US-20100278768-A1 | Compounds and Methods for Inhibiting Axillary Malodour | GIVAUDAN SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-7264956-B2 | N-alpha-acyl-glutamine-aminoacylase for identifying enzyme inhibitors which prevent/supress sweating odor; deodorants | GIVAUDAN SA (CH) | 2007-09-04 | — | — | US | disclosed |
| EP-1811034-A2 | Compounds and method for inhibiting axillary malodour | Givaudan SA (CH) | 2007-07-25 | — | — | EP | disclosed |
| US-20040241795-A1 | Compounds and methods for inhibiting axillary malodour | GIVAUDAN SA (CH) | 2004-12-02 | — | — | US | disclosed |
| EP-1387891-A2 | COMPOUNDS AND METHODS FOR INHIBITING AXILLARY MALODOUR | Givaudan SA (CH) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002092024-A2 | COMPOUNDS AND METHODS FOR INHIBITING AXILLARY MALODOUR | GIVAUDAN SA (CH) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318290-A1 | Compounds and Methods for Inhibiting Axillary Malodour | TYR, AOX1, APEH | KMT2A 4033/4885SMN1; SMN2 4181/4885MEN1 3655/4885 |
| US-20100278768-A1 | Compounds and Methods for Inhibiting Axillary Malodour | TYR, AOX1, APEH | KMT2A 4033/4885SMN1; SMN2 4181/4885MEN1 3655/4885 |
| US-20040241795-A1 | Compounds and methods for inhibiting axillary malodour | AOX1, TYR, ME1 | KMT2A 4278/4885SMN1; SMN2 3802/4885MEN1 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.