Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | CYCS | P99999 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351897 | 0.96 | STAT3 (0.45) | STAT3STAT1TOP1ABCG2BRD4 | |
| SCHEMBL1596068 | 0.95 | STAT3 (0.47) | STAT3STAT1TOP1ABCG2CYCS | |
| SCHEMBL1597373 | 0.91 | STAT3 (0.43) | STAT3STAT1TOP1ABCG2CYCS | |
| SCHEMBL5445020 | 0.89 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL9095058 | 0.88 | STAT3 (0.45) | STAT3STAT1BRD4MAPTALOX15 | |
| SCHEMBL5034725 | 0.87 | STAT3 (0.47) | STAT3STAT1TOP1ABCG2CYCS | |
| SCHEMBL6092415 | 0.85 | STAT3 (0.43) | STAT3STAT1TOP1ABCG2CYCS | |
| SCHEMBL3125425 | 0.82 | STAT3 (0.49) | STAT3STAT1TOP1CYCS | |
| SCHEMBL351525 | 0.81 | BRD4 (0.35) | STAT3STAT1BRD4MAPTALOX15 | |
| SCHEMBL6094135 | 0.81 | STAT3 (0.45) | STAT3STAT1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | claimed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | claimed |
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-28 | — | — | US | claimed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | claimed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | claimed |
| US-8952357-B2 | Cytochrome c552 color imaging element and method of manufacturing the same, cytochrome c552 photosensor and method of manufacturing the same, cytochrome c552 photoelectric transducer and method of manufacturing the same, and cytochrome c552 electronic device | SONY CORPORATION (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-8178872-B2 | Molecular device, imaging device, photosensor, and electronic apparatus | SONY CORPORATION (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20120012823-A1 | COLOR IMAGING ELEMENT AND METHOD OF MANUFACTURING THE SAME, PHOTOSENSOR AND METHOD OF MANUFACTURING THE SAME, PHOTOELECTRIC TRANSDUCER AND METHOD OF MANUFACTURING THE SAME, AND ELECTRONIC DEVICE | SONY CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | disclosed |
| US-7919615-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100264409-A1 | MOLECULAR DEVICE, IMAGING DEVICE, PHOTOSENSOR, AND ELECTRONIC APPARATUS | SONY CORPORATION (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-28 | — | — | US | disclosed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20080283122-A1 | Beta-Substituted Porphyrins | CAMPBELL WAYNE MASON | 2008-11-20 | — | — | US | disclosed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, DHPS, FDPS | STAT3 3755/4885STAT1 3957/4885TOP1 1571/4885 |
| US-20080283122-A1 | Beta-Substituted Porphyrins | PPOX, HMBS, CRY1 | STAT3 3336/4885STAT1 4389/4885TOP1 2190/4885 |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, ALAD, UROD | STAT3 4123/4885STAT1 4328/4885TOP1 1556/4885 |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | DHPS, NOTUM, DOHH | STAT3 4298/4885STAT1 4505/4885TOP1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.