SCHEMBL7538541

SCHEMBL7538541

COCCOC(=O)/C=C/C(=O)OC(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.53
ATM Q13315 1/20 0.44
CA12 O43570 1/20 0.39
AKR1B10 O60218 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
AKR1B1 P15121 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
MAPT P10636 2/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890674 0.85 ATM (0.56) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL5974049 0.85 ATM (0.56) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL403340 0.85 ATM (0.56) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2608260 0.83 TSHR (0.53) HCAR2ATMCA12AKR1B10CA1
SCHEMBL3516591 0.82 HCAR2 (0.62) HCAR2ATMCA12AKR1B10CA1
SCHEMBL9135761 0.82 HCAR2 (0.55) HCAR2ATMCA12AKR1B10CA1
SCHEMBL3516696 0.82 HCAR2 (0.55) HCAR2ATMCA12AKR1B10CA1
SCHEMBL3516369 0.81 HCAR2 (0.53) HCAR2ATMCA12AKR1B10CA1
SCHEMBL6522602 0.81 HCAR2 (0.39) HCAR2ATMCA12CA1CA2
SCHEMBL7536969 0.81 HCAR2 (0.53) HCAR2ATMCA12AKR1B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020190818-A1 High frequency band pass filter TDK CORPORATION (JP) 2002-12-19 US disclosed
EP-0788118-B1 Low dielectric polymer and film, substrate and electronic part using the same TDK CORP (JP) 2002-11-20 EP disclosed
US-5914283-A FUMARIC ACID DIESTER MONOMER-CONTAINING POLYMER FILM; HEAT RESISTANCE, WEATHER RESISTANCE TDK CORPORATION (JP) 1999-06-22 US disclosed
EP-0788118-A1 Low dielectric polymer and film, substrate and electronic part using the same TDK Corporation (JP) 1997-08-06 EP disclosed