Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520043 | 0.94 | ACHE (0.43) | ACHEADRA1ALMNAESR1ADORA3 | |
| SCHEMBL3520473 | 0.94 | ACHE (0.43) | ACHEADRA1ALMNAESR1ADORA3 | |
| SCHEMBL779538 | 0.84 | F7 (0.37) | LMNAADORA3KCNH2MEN1KMT2A | |
| SCHEMBL3517051 | 0.82 | ADRA1A (0.36) | ACHEADRA1ALMNAESR1ADORA3 | |
| SCHEMBL779301 | 0.78 | F7 (0.38) | LMNAADORA3KCNH2MEN1KMT2A | |
| SCHEMBL778474 | 0.72 | F7 (0.39) | LMNAADORA3KCNH2MEN1KMT2A | |
| SCHEMBL28863431 | 0.72 | FAAH (0.47) | LMNAADORA3KCNH2ENPP2MEN1 | |
| SCHEMBL16505610 | 0.71 | FAAH (0.37) | LMNAADORA3KCNH2MEN1KMT2A | |
| SCHEMBL781122 | 0.71 | ADRB2 (0.36) | — | |
| SCHEMBL28181175 | 0.71 | ACHE (0.42) | ACHEADRA1ALMNAESR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119303108-A | Method for recovering microglia and astrocytes and application thereof | 南卡罗来纳大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-117545475-A | Brain-targeted antibody nanoparticles for treatment of neurodegenerative diseases | 南卡罗来纳大学 | 2024-02-09 | — | — | CN | disclosed |
| US-8765417-B2 | Method of elongating DNA through immobilizing primer DNA chains on a substrate, a method of amplifying a DNA chain | SUMITOMO BAKELITE CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-1820857-B1 | DNA CHAIN ELONGATION METHOD, DNA CHAIN AMPLIFICATION METHOD AND MICROARRAY FOR DNA CHAIN ELONGATION | SUMITOMO BAKELITE CO (JP) | 2010-09-22 | — | — | EP | disclosed |
| US-20080032348-A1 | Method of Elongating Dna Chain, Method of Amplifying Dna Chain, and Microarray for Dna Chain Elongation | DNA CHIP RESEARCH INC. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1820857-A1 | DNA CHAIN ELONGATION METHOD, DNA CHAIN AMPLIFICATION METHOD AND MICROARRAY FOR DNA CHAIN ELONGATION | Sumitomo Bakelite Company, Limited (JP) | 2007-08-22 | — | — | EP | disclosed |