Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515113 | 0.93 | SLC9A1 (0.55) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL628179 | 0.71 | SLC9A1 (0.48) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL29788159 | 0.68 | SLC9A1 (0.57) | SLC9A1KEAP1MAPTPOLBKCNMA1 | |
| SCHEMBL5052035 | 0.68 | SLC9A1 (0.44) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL29720118 | 0.66 | SLC9A1 (1.00) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL11959496 | 0.66 | SLC9A1 (0.56) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL170155 | 0.66 | SLC9A1 (1.00) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL11044976 | 0.66 | SLC9A1 (0.56) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL2820092 | 0.66 | SLC9A1 (0.50) | SLC9A1KEAP1MAPTPOLBMAPK1 | |
| SCHEMBL3072391 | 0.65 | SLC9A1 (0.60) | SLC9A1KEAP1MAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292436-A1 | METHOD FOR PRODUCING BIVALIRUDIN | SHANGHAI AMBIOPHARM, INC. (CN) | 2010-11-18 | — | — | US | claimed |
| US-20170029467-A1 | METHOD OF PRODUCING BIVALIRUDIN | AMBIOPHARM, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20110319594-A1 | METHOD FOR PRODUCING BIVALIRUDIN | SHANGHAI AMBIOPHARM, INC. (CN) | 2011-12-29 | — | — | US | disclosed |
| US-20100292436-A1 | METHOD FOR PRODUCING BIVALIRUDIN | SHANGHAI AMBIOPHARM, INC. (CN) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319594-A1 | METHOD FOR PRODUCING BIVALIRUDIN | ARGLU1, SERPINC1, PSMA6 | SLC9A1 4311/4885KEAP1 3296/4885MAPT 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.