Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588938 | 0.77 | TSHR (0.39) | POLBTSHRMAPK1GAAALDH1A1 | |
| SCHEMBL7889055 | 0.72 | CA4 (0.41) | KCNN4ACHEPOLBNPSR1TSHR | |
| Benzene SCHEMBL28036071 | 0.66 | KCNN4 (0.48) | KCNN4CES1SRCMAPTCES2 | |
| Toluene SCHEMBL27497852 | 0.64 | ACHE (0.46) | KCNN4CES1MAPTCES2ACHE | |
| SCHEMBL29281053 | 0.64 | ELANE (0.51) | KCNN4SRCMAPTCTRB1MEN1 | |
| SCHEMBL1255890 | 0.63 | ELANE (0.47) | CES1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL784101 | 0.63 | KCNN4 (0.47) | KCNN4CES1SRCMAPTCES2 | |
| SCHEMBL4269419 | 0.63 | CES1 (0.42) | KCNN4CES1SRCCES2ACHE | |
| SCHEMBL4832864 | 0.63 | HDAC1 (0.44) | KCNN4CES1MAPTPDK1PDK2 | |
| SCHEMBL8215977 | 0.63 | CES1 (0.42) | KCNN4CES1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |