Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267223 | 0.84 | CES1 (0.42) | CES1HDAC6DAOTSHRNAPRT | |
| SCHEMBL7052777 | 0.81 | CES1 (0.39) | CES1HDAC6DAOTSHRNAPRT | |
| SCHEMBL4270183 | 0.80 | CYP1A2 (0.38) | CES1DAOTSHRNAPRTKCNN4 | |
| SCHEMBL204167 | 0.72 | ALDH1A1 (0.42) | CES1DAOTSHRNAPRTCES2 | |
| SCHEMBL1255890 | 0.68 | ELANE (0.47) | CES1HDAC1HDAC2 | |
| SCHEMBL4266491 | 0.68 | CES1 (0.42) | CES1HDAC6KCNN4HDAC1HDAC2 | |
| SCHEMBL1053845 | 0.68 | ELANE (0.43) | CES1DAOTSHRNAPRTCES2 | |
| SCHEMBL10946374 | 0.67 | ELANE (0.46) | CES1HDAC1HDAC2 | |
| SCHEMBL28404237 | 0.66 | ELANE (0.47) | CES1HDAC6TSHRNAPRTACHE | |
| SCHEMBL1051530 | 0.65 | ACHE (0.41) | CES1KCNN4HDAC1HDAC2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |