Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Azelaic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL352890 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL28178132 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9850543 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Octanedioate SCHEMBL29154819 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Sebacic Acid SCHEMBL30734379 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL11145819 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL28198648 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9859986 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL17727985 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9739994 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535047-B | Heat-sealable composite polyester film | DUPONT TEIJIN FILMS US LTD | 2012-05-16 | — | — | CN | claimed |
| CN-101384430-B | Polyester film | DUPONT TEIJIN FILMS U.S. L.P. (US) | 2011-12-21 | — | — | CN | claimed |
| CN-101535047-A | Heat-sealable composite polyester film | DUPONT TEIJIN FILMS US LTD (US) | 2009-09-16 | — | — | CN | claimed |
| CN-101384430-A | Polyester film | DUPONT TEIJIN FILMS US LTD (US) | 2009-03-11 | — | — | CN | claimed |
| WO-2023190413-A1 | MODIFIED POLYESTER-BASED RESIN, ADHESIVE RESIN COMPOSITION, AND LAMINATE | 三菱ケミカル株式会社 | 2023-10-05 | — | — | WO | disclosed |
| CN-108698394-A | multilayer film for vacuum skin packaging, packaging method and package obtained thereby | 克里奥瓦克公司 | 2018-10-23 | — | — | CN | disclosed |
| US-9447274-B2 | Biologically-degradable polyester mixture | BASF SE (DE) | 2016-09-20 | — | — | US | disclosed |
| CN-103153619-B | Thermoformable copolyester laminates | DUPONT TEIJIN FILMS U.S. L.P. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-101939165-B | Dual ovenable food package having a thermoformable polyester film lid | DUPONT TEIJIN FILMS US LTD | 2015-05-13 | — | — | CN | disclosed |
| CN-102421600-B | Transparent conductive composite films | DUPONT TEIJIN FILMS US LTD PARTNERSHIP | 2015-03-25 | — | — | CN | disclosed |
| CN-102066087-B | Anti-microbial polymeric film and method of manufacture of said film | DUPONT TEIJIN FILMS US LTD PARTNERSHIP | 2014-05-14 | — | — | CN | disclosed |
| US-8569407-B2 | Biodegradable material composed of a polymer comprising a porous metal-organic framework | BASF SE (DE) | 2013-10-29 | — | — | US | disclosed |
| CN-100537229-C | Multi-layer polymeric film for packaging ovenable meals | DUPONT TEIJIN FILMS U S LTD (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101384430-A | Polyester film | DUPONT TEIJIN FILMS US LTD (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101384431-A | Coextruded heat-shrinkable polyester film | CRYOVAC INC (US) | 2009-03-11 | — | — | CN | disclosed |
| US-20080281018-A1 | Biologically-Degradable Polyester Mixture | BASF AKTIENGESLLSCHAFT (DE) | 2008-11-13 | — | — | US | disclosed |
| CN-101052303-A | Antimicrobial polymer film | DUPOUNT TEIJIN FILMS US LTD PA (US) | 2007-10-10 | — | — | CN | disclosed |
| CN-1950837-A | Polymeric film substrate for use in radio-frequency responsive tags | DUPONT TEIJIN FILMS US LTD (US) | 2007-04-18 | — | — | CN | disclosed |
| CN-1292892-C | Heat-sealable and shrinkable multilayer polymeric film | DUPONT TEIJIN FILMS US LTD (US) | 2007-01-03 | — | — | CN | disclosed |
| CN-1622878-A | Heat-sealable and shrinkable multi-layer polymeric film | DUPONT TEIJIN FILMS US LTD (US) | 2005-06-01 | — | — | CN | disclosed |