Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28178132 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9850543 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Octanedioate SCHEMBL29154819 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Sebacic Acid SCHEMBL30734379 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL11145819 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Azelaic Acid SCHEMBL351913 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL28198648 | 1.00 | LMNA (0.60) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9859986 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL17727985 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 | |
| Terephthalic Acid SCHEMBL9739994 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112980381-A | High-temperature-resistant water-based environment-friendly adhesive and preparation method thereof | 广州菩曦环保科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-102877340-A | Coated mooring rope made of high-molecular-weight polyethylene fibers | TAO XIANGCHUAN | 2013-01-16 | — | — | CN | claimed |
| CN-112980381-A | High-temperature-resistant water-based environment-friendly adhesive and preparation method thereof | 广州菩曦环保科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-105440268-B | A kind of aliphatic aromatic PLA segmented copolymer | 中国科学院长春应用化学研究所 | 2018-02-13 | — | — | CN | disclosed |
| CN-105440267-B | A kind of aliphatic aromatic PLA random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2018-02-13 | — | — | CN | disclosed |
| CN-107459783-A | A kind of common sebacate resin combination of polyester terephthalate | 金发科技股份有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-105542134-B | A kind of lactyl aliphatic aromatic random copolymer | 中国科学院长春应用化学研究所 | 2017-11-28 | — | — | CN | disclosed |
| US-9447274-B2 | Biologically-degradable polyester mixture | BASF SE (DE) | 2016-09-20 | — | — | US | disclosed |
| CN-105622911-A | Unsaturated aliphatic-aromatic-polylactic acid block copolymer | CHANGCHUN INST APPLIED CHEMISTRY CAS | 2016-06-01 | — | — | CN | disclosed |
| EP-2104712-B1 | POLYMERIC COMPOSITION COMPRISING POLYOLEFINS AND ALIPHATIC-AROMATIC COPOLYESTERS | NOVAMONT SPA (IT) | 2014-06-25 | — | — | EP | disclosed |
| CN-101657504-B | Polymeric composition comprising polyolefins and aliphatic-aromatic copolyesters | NOVAMONT SPA | 2014-01-08 | — | — | CN | disclosed |
| CN-101657504-A | Polymeric composition comprising polyolefins and aliphatic-aromatic copolyesters | NOVAMONT SPA IT | 2010-02-24 | — | — | CN | disclosed |
| EP-2104712-A1 | POLYMERIC COMPOSITION COMPRISING POLYOLEFINS AND ALIPHATIC-AROMATIC COPOLYESTERS | Novamont S.p.A. (IT) | 2009-09-30 | — | — | EP | disclosed |
| US-20080281018-A1 | Biologically-Degradable Polyester Mixture | BASF AKTIENGESLLSCHAFT (DE) | 2008-11-13 | — | — | US | disclosed |
| WO-2008074878-A1 | POLYMERIC COMPOSITION COMPRISING POLYOLEFINS AND ALIPHATIC-AROMATIC COPOLYESTERS | NOVAMONT S.P.A. (IT) | 2008-06-26 | — | — | WO | disclosed |
| US-20020077397-A1 | Non-staining coating composition | SK KAKEN CO., LTD. | 2002-06-20 | — | — | US | disclosed |
| CN-1173327-A | Production of solid drug forms | BASF AG (DE) | 1998-02-18 | — | — | CN | disclosed |
| EP-0534692-B1 | Corrosion inhibitor combinations and process for inhibiting corrosion in heat transfer fluids | TEXACO DEVELOPMENT CORP (US) | 1996-01-17 | — | — | EP | disclosed |
| EP-0534692-A1 | Corrosion inhibitor combinations and process for inhibiting corrosion in heat transfer fluids | TEXACO DEVELOPMENT CORPORATION (US) | 1993-03-31 | — | — | EP | disclosed |
| US-4171421-A | FROM AROMATIC AND ALIPHATIC DICARBOXYLIC ACIDS AND UNSUBITITUTED BISPHENOLS | CIBA-GEIGY CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |