Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57076 | 0.94 | ALDH1A1 (0.54) | ALDH1A1PKMMAPK1HSD17B10CYP1A2 | |
| Ethylene Glycol SCHEMBL5092840 | 0.88 | PTGS1 (0.46) | ALDH1A1MAPK1HSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL5200032 | 0.85 | ALDH1A1 (0.50) | ALDH1A1PKMMAPK1HSD17B10CYP1A2 | |
| SCHEMBL501046 | 0.81 | PTGS1 (0.50) | ALDH1A1MAPK1HSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL7463384 | 0.79 | PTGS1 (0.58) | ALDH1A1PKMHSD17B10POLBSMN1; SMN2 | |
| Ethylene Glycol SCHEMBL27986613 | 0.78 | TSHR (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5698008 | 0.78 | PTGS1 (0.61) | ALDH1A1PKMHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL1618771 | 0.78 | PTGS1 (0.61) | ALDH1A1PKMHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL7259687 | 0.78 | PTGS1 (0.61) | ALDH1A1PKMHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL5698003 | 0.78 | PTGS1 (0.61) | ALDH1A1PKMHSD17B10POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104046600-A | Novel purpose of multi-arm polyethylene glycol (PEG) modification agent and use of multi-arm PEG modification agent in L-asparaginasum modification | ZONHON BIOPHARMA INST INC | 2014-09-17 | — | — | CN | claimed |
| EP-2654776-A1 | USE OF PEGYLATED RECOMBINANT HUMAN ARGINASE FOR TREATMENT OF LEUKEMIA | Cheng, Ning Man (CN) | 2013-10-30 | — | — | EP | claimed |
| US-8217166-B2 | Polyethylene glycolated superoxide dismutase mimetics | GALERA THERAPEUTICS, LLC (US) | 2012-07-10 | — | — | US | claimed |
| WO-2012085793-A1 | USE OF PEGYLATED RECOMBINANT HUMAN ARGINASE FOR TREATMENT OF LEUKEMIA | CHENG NING MAN (CN) | 2012-06-28 | — | — | WO | claimed |
| US-20100303893-A1 | NOVEL COMPOUND FOR TREATMENT OF TUMOR | PROTGEN LTD. (CN) | 2010-12-02 | — | — | US | claimed |
| US-20100285103-A1 | MEDICAMENT FOR TREATMENT OF TUMORS AND THE USE THEREOF | PROTGEN LTD. (CN) | 2010-11-11 | — | — | US | claimed |
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2008-12-25 | — | — | US | claimed |
| WO-2006069326-A2 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | METAPHORE PHARMACEUTICALS, INC. (US) | 2006-06-29 | — | — | WO | claimed |
| EP-1322234-A2 | RESORBABLE ANASTOMOSIS STENTS AND PLUGS | Cohesion Technologies, Inc. (US) | 2003-07-02 | — | — | EP | claimed |
| US-20020052572-A1 | Resorbable anastomosis stents and plugs and their use in patients | COHESION TECHNOLOGIES, INC. | 2002-05-02 | — | — | US | claimed |
| WO-2002024114-A2 | RESORBABLE ANASTOMOSIS STENTS AND PLUGS | COHESION TECHNOLOGIES, INC. (US) | 2002-03-28 | — | — | WO | claimed |
| US-9150837-B2 | Polyethylene glycolated superoxide dismutase mimetics | GALERA LABS LLC (US) | 2015-10-06 | — | — | US | disclosed |
| CN-104046600-A | Novel purpose of multi-arm polyethylene glycol (PEG) modification agent and use of multi-arm PEG modification agent in L-asparaginasum modification | ZONHON BIOPHARMA INST INC | 2014-09-17 | — | — | CN | disclosed |
| US-20130287696-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2013-10-31 | — | — | US | disclosed |
| US-20120301403-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-8217166-B2 | Polyethylene glycolated superoxide dismutase mimetics | GALERA THERAPEUTICS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| CN-101522714-A | Ige-retargeting, function-altering molecules (ERFAM) for treatment of allergic diseases | ST MARY S HOSPITAL NAT HEALTH (GB) | 2009-09-02 | — | — | CN | disclosed |
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2008-12-25 | — | — | US | disclosed |
| WO-2006069326-A2 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | METAPHORE PHARMACEUTICALS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | ALDH1A1 219/4885PKM 2014/4885MAPK1 3632/4885 |
| US-20120301403-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | ALDH1A1 226/4885PKM 1715/4885MAPK1 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.