Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733865 | 0.95 | ALOX15 (0.51) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL27189982 | 0.93 | ALOX15 (0.50) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL4007510 | 0.85 | ALOX15 (0.53) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| SCHEMBL3451504 | 0.85 | SLC6A1 (0.46) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| SCHEMBL870123 | 0.85 | SLC6A1 (0.46) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| SCHEMBL870122 | 0.85 | SLC6A1 (0.46) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL29891896 | 0.84 | EPHX1 (0.49) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL2767309 | 0.83 | SLC6A1 (0.44) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL2768568 | 0.83 | SLC6A1 (0.44) | ALOX15TSHRCHRM3CHRM1CHRM2 | |
| SCHEMBL9431190 | 0.82 | TDP1 (0.52) | EPHX1CKS1BSKP1SKP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684091-A | cannabinoid receptor ligands | SCHERING CORP | 2010-03-31 | — | — | CN | disclosed |
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |
| CN-100567266-C | Cannabinoid receptor ligands | SCHERING CORP (US) | 2009-12-09 | — | — | CN | disclosed |
| US-7071213-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050282861-A1 | Cannabinoid receptor ligands | MERCK SHARP & DOHME CORP. | 2005-12-22 | — | — | US | disclosed |
| CN-1585749-A | Cannabinoid receptor ligands | SCHERING CORP (US) | 2005-02-23 | — | — | CN | disclosed |
| EP-1444203-A1 | CANNABINOID RECEPTOR LIGANDS | Schering Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | SCHERING CORPORATION | 2004-01-15 | — | — | US | disclosed |
| WO-2003042174-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | IL5, IL2, TLR1 | ALOX15 903/4885TSHR 4120/4885CHRM3 1383/4885 |
| US-20050282861-A1 | Cannabinoid receptor ligands | CNR1, CNR2, GPR18 | ALOX15 695/4885TSHR 972/4885CHRM3 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.