Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588619 | 0.83 | L3MBTL1 (0.70) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3960184 | 0.81 | DAO (0.48) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6211351 | 0.81 | L3MBTL1 (0.58) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10638684 | 0.79 | S1PR1 (0.41) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22711381 | 0.79 | HDAC8 (0.63) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7205892 | 0.79 | F2 (0.52) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15113608 | 0.79 | S1PR1 (0.39) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20786824 | 0.79 | KDM4E (0.49) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2226439 | 0.79 | NPSR1 (0.51) | L3MBTL1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL2872059 | 0.77 | GSK3B (0.67) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118448723-A | Sodium ion battery electrolyte, preparation method thereof and sodium ion battery | 广州鹏辉能源科技股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-115425292-B | High-temperature-resistant electrolyte, secondary battery and application thereof | 华中科技大学 | 2024-07-23 | — | — | CN | claimed |
| CN-115425292-A | High-temperature-resistant electrolyte, secondary battery and application thereof | 华中科技大学 | 2022-12-02 | — | — | CN | claimed |
| CN-118448723-A | Sodium ion battery electrolyte, preparation method thereof and sodium ion battery | 广州鹏辉能源科技股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-118448723-A | Sodium ion battery electrolyte, preparation method thereof and sodium ion battery | 广州鹏辉能源科技股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115425292-B | High-temperature-resistant electrolyte, secondary battery and application thereof | 华中科技大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-08-17 | — | — | US | disclosed |
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-08-17 | — | — | US | disclosed |
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-0879223-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | Centre Europeen de Bioprospective -CEB (FR) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997026237-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CENTRE EUROPEEN DE BIOPROSPECTIVE - CEB (FR) | 1997-07-24 | — | — | WO | disclosed |
| EP-0245835-B1 | NOVEL THIOPHENE DERIVATIVES AND METHODS FOR PRODUCING THE SAME | SEITETSU KAGAKU CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4341957-A | Fluorescent antibody composition for immunofluorometric assay | ANALYTICAL RADIATION CORPORATION (US) | 1982-07-27 | — | — | US | disclosed |
| US-4153610-A | Process for producing 5-carboxy-2-acetylthiophene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-05-08 | — | — | US | disclosed |
| US-4130566-A | Process for producing 5-carboxy-2-acetylthiophene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV5 | L3MBTL1 3924/4885MAPT 365/4885NPC1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.