SCHEMBL352342

SCHEMBL352342

NC(=O)CC[C@H](N)C(=O)OC(=O)CC[C@H](N)C(=O)OC(=O)[C@@H](N)CCC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
KMT2A Q03164 1/20 0.52
DPP4 P27487 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
SLC1A1 P43005 2/20 0.34
GRM8 O00222 1/20 0.34
GRM6 O15303 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GSR P00390 1/20 0.34
CYP1A2 P05177 1/20 0.34
GRIK1 P39086 1/20 0.34
GRM5 P41594 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
SLC1A3 P43003 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28571398 1.00 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL711607 0.92 ALOX15 (0.60) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2443865 0.91 KMT2A (0.68) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL9452863 0.89 ALOX15 (0.48) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5187828 0.89 ALOX15 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL17559225 0.88 ALOX15 (0.42) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL869883 0.86 ALOX15 (0.50) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5524401 0.85 ALOX15 (0.48) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL3178198 0.84 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1674762 0.84 SLC1A1 (0.54) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117969859-A Metabolic biomarker for polycystic ovary syndrome and application thereof 山东大学 2024-05-03 CN claimed
US-20090269806-A1 PROCESS FOR PRODUCING DIPEPTIDES KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-10-29 US claimed
WO-2003002135-A2 HERBAL COMPOSITION PRETORIUS ANDRIES PHILIPPUS (ZA) 2003-01-09 WO claimed
EP-0514509-B1 COMPOSITION AND ITS PREPARATION PROCESS USING ANTIGEN CONJUGATED TO ENZYMATIC ACTIVITY FOR IMMUNOLOGICAL DIAGNOSIS AND CHAGAS' DISEASE IMMUNOLOGICAL DIAGNOSIS KITS, FOR INDIVIDUAL AND EPIDEMIOLOGICAL APPLICATION, BASED ON THAT COMPOSITION FUNDACAO OSWALDO CRUZ (BR) 2000-09-20 EP claimed
US-12583896-B2 Caged-degron-based molecular feedback circuits and methods of using the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-24 US disclosed
CN-113194742-B Antagonists of T2R54, compositions thereof and uses thereof 弗门尼舍公司 2024-09-27 CN disclosed
CN-117969859-B Metabolic biomarker for polycystic ovary syndrome and application thereof 山东大学 2024-09-06 CN disclosed
CN-117969859-A Metabolic biomarker for polycystic ovary syndrome and application thereof 山东大学 2024-05-03 CN disclosed
US-20220119467-A1 CAGED-DEGRON-BASED MOLECULAR FEEDBACK CIRCUITS AND METHODS OF USING THE SAME UNIVERSITY OF WASHINGTON 2022-04-21 US disclosed
US-20220119466-A1 SYNTHETIC MOLECULAR FEEDBACK CIRCUITS AND METHODS OF USING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-04-21 US disclosed
US-20220073565-A1 DE NOVO DESIGN OF PROTEIN SWITCHES FOR TUNABLE CONTROL OF PROTEIN DEGRADATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-03-10 US disclosed
CN-113853384-A Novel design of a protein switch for the tuneable control of protein degradation 华盛顿大学 2021-12-28 CN disclosed
US-5302717-A Preparation of urethane and carbonate products MONSANTO COMPANY (US) 1994-04-12 US disclosed
EP-0576669-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1994-01-05 EP disclosed
US-5273885-A Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine SYNTEX (U.S.A.) INC. (US) 1993-12-28 US disclosed
US-5260473-A Reaction of alcohol and carbon dioxide in aprotic solvent and strong amidine or guanidine base MONSANTO COMPANY (US) 1993-11-09 US disclosed
EP-0556538-A1 Blocked tricarbamate compounds MONSANTO COMPANY (US) 1993-08-25 EP disclosed
WO-1993013794-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1993-07-22 WO disclosed
US-5223638-A Reacting primary or secondary amine with carbon dioxide in presence of strong amidine or guanidine base to form ammonium carbamate salt, reacting in polar aprotic solvent with primary or secondary hydrocarbyl halide MONSANTO COMPANY (US) 1993-06-29 US disclosed
EP-0511948-A2 Preparation of urethane and carbonate products MONSANTO COMPANY (US) 1992-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583896-B2 Caged-degron-based molecular feedback circuits and methods of using the same RPRD2, STUB1, SSU72 ALOX15 4749/4885BLM 586/4885PMP22 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.