Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Propylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2389986 | 0.90 | — | — | |
| Sulfuric Acid SCHEMBL27612656 | 0.90 | BLM (0.47) | — | |
| Sulfuric Acid SCHEMBL11438607 | 0.90 | BLM (0.47) | — | |
| Ethylamine SCHEMBL6138422 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL27481010 | 0.86 | BLM (0.50) | — | |
| Ethylenediamine SCHEMBL9351771 | 0.86 | — | — | |
| Propylamine SCHEMBL25423723 | 0.85 | LMNA (0.39) | — | |
| Butylamine SCHEMBL3521071 | 0.85 | APP (0.48) | — | |
| Propylamine SCHEMBL11599473 | 0.84 | — | — | |
| SCHEMBL3526719 | 0.83 | DNM1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283568-A | Preparation method of sorbate | 南通新宙邦电子材料有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283568-A | Preparation method of sorbate | 南通新宙邦电子材料有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-102529310-A | Lithographic printing plate precursor and lithographic printing method | FUJIFILM CORP | 2012-07-04 | — | — | CN | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| CN-101346369-A | Pyrazinoylguanidine compounds useful in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2009-01-14 | — | — | CN | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| EP-1968969-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007071396-A2 | PYRAZINOYLGUANIDINE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| CN-1107699-A | Treatment of incontinence | LILLY CO ELI (US) | 1995-09-06 | — | — | CN | disclosed |
| CN-1019113-B | Process for preparing 3-arylhydrido-3-substituted propanamines | LILLY CO ELI (US) | 1992-11-18 | — | — | CN | disclosed |
| CN-87108175-A | The propylamine that 3-aryloxy-3-replaces | — | 1988-07-06 | — | — | CN | disclosed |