SCHEMBL3528979

SCHEMBL3528979

Cc1ccccc1OCCN

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
HTR1B P28222 1/20 0.55
HPGD P15428 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
RAB9A P51151 2/20 0.53
TP53 P04637 1/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
ALOX15 P16050 1/20 0.51
DRD2 P14416 2/20 0.50
DRD4 P21917 2/20 0.50
NPC1 O15118 1/20 0.50
TSHR P16473 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
AOC2 O75106 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
SCN4A P35499 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10926266 0.89 HTR1B (0.56) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL1592876 0.86 TDP1 (0.60) KDM4EHPGDSMN1; SMN2RAB9ATDP1
SCHEMBL15923371 0.86 ALDH1A1 (0.57) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL12230884 0.86 ALDH1A1 (0.57) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL2804367 0.86 ALDH1A1 (0.57) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL11679951 0.84 CYP2D6 (0.61) KDM4EHPGDSMN1; SMN2RAB9AMAPK1
SCHEMBL9808080 0.84 ALDH1A1 (0.62) KDM4EHPGDSMN1; SMN2RAB9AMAPK1
SCHEMBL31050988 0.84 KDM4E (0.95) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL8834938 0.84 KDM4E (0.95) KDM4EHTR1BHPGDSMN1; SMN2RAB9A
SCHEMBL7415579 0.83 HTR1B (0.62) KDM4EHTR1BHPGDSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US claimed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US claimed
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain LIN, TONG-HO (TW) 2003-03-20 US claimed
EP-0054132-B1 PYRIMIDONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-10-10 EP claimed
US-4379788-A HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-04-12 US claimed
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US disclosed
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2025-07-22 US disclosed
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2024-08-08 US disclosed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US disclosed
WO-2022148879-A1 QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF ACKR3 STICHTING VU (NL) 2022-07-14 WO disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-4503067-A HYPOTENSIVE, ANGINA PECTORIS BOEHRINGER MANNHEIM GMBH (DE) 1985-03-05 US disclosed
EP-0040591-B1 PYRIDOXINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE S.A. SANOFI - LABAZ N.V. (BE) 1983-06-22 EP disclosed
US-4379788-A HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-04-12 US disclosed
US-4374841-A HYPOTENSIVE, ADRENERGIC BLOCKING, AND CARDIOTONIC AGENTS; CENTRAL DEPRESSANTS S. A. LABAZ N.V. (BE) 1983-02-22 US disclosed
EP-0004920-B1 DERIVATIVES OF CARBAZOLYL-4-OXYPROPANOLAMINE, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM Roche Diagnostics GmbH (DE) 1981-08-05 EP disclosed
EP-0004920-A1 Derivatives of carbazolyl-4-oxypropanolamine, methods for their preparation and medicines containing them Roche Diagnostics GmbH (DE) 1979-10-31 EP disclosed
US-4119729-A TREATMENT OF HYPERTENSION MEAD JOHNSON & COMPANY (US) 1978-10-10 US disclosed
US-4067904-A ANTIARRHYTHMIA, HYPOTENSIVE MEAD JOHNSON & COMPANY (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 KDM4E 3830/4885HTR1B 1932/4885HPGD 2236/4885
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 KDM4E 3830/4885HTR1B 1932/4885HPGD 2236/4885
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain KCNH2, ADRB3, KCNH3 KDM4E 3423/4885HTR1B 195/4885HPGD 3166/4885
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 KDM4E 3830/4885HTR1B 1932/4885HPGD 2236/4885
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 KDM4E 3830/4885HTR1B 1932/4885HPGD 2236/4885
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 KDM4E 3830/4885HTR1B 1932/4885HPGD 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.