Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230884 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL15923371 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL10926266 | 0.92 | HTR1B (0.56) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL9808080 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL11021541 | 0.86 | RAB9A (0.47) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL3528979 | 0.86 | KDM4E (0.68) | ALDH1A1CYP2D6CYP2C19LMNAMAPK1 | |
| SCHEMBL11019776 | 0.85 | HTR1B (0.46) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL11679951 | 0.83 | CYP2D6 (0.61) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 | |
| SCHEMBL11020601 | 0.83 | HTR1B (0.45) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL22207086 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475685-B2 | Particle and near-field optical waveguide | KABUSHIKI KAISHA TOSHIBA (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | F2, AHR, CRY1 | ALDH1A1 2720/4885CYP2D6 297/4885CYP2C19 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.