Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SLC8A1 | P32418 | 11/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536263 | 0.93 | SLC8A1 (0.41) | HTR6MAOBCA2CA5ASLC8A1 | |
| SCHEMBL4372458 | 0.72 | ESR1 (0.56) | HTR6SLC8A1 | |
| SCHEMBL24984291 | 0.72 | STING1 (0.41) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL24983789 | 0.72 | STING1 (0.41) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL24983373 | 0.72 | STING1 (0.41) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL24983614 | 0.70 | MAOB (0.39) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL18427327 | 0.70 | MAOB (0.39) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL6495431 | 0.69 | HTR6 (0.61) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL10638743 | 0.69 | ITGB3 (0.52) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL10477669 | 0.68 | MEN1 (0.50) | MAOBMAOANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700646-B2 | Compounds for use in the treatment of infection | THE UNIVERSITY OF LONDON, SCHOOL OF PHARMACY (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20070021384-A1 | Compounds for use in the treatment of infection | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021384-A1 | Compounds for use in the treatment of infection | C9, APEH, GRHPR | HTR6 2174/4885MAOB 797/4885CA2 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.