Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 11/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530893 | 0.93 | HTR6 (0.42) | SLC8A1HTR6MAOBCA2CA5A | |
| SCHEMBL4372458 | 0.80 | ESR1 (0.56) | SLC8A1HTR6GRIN1KCNH2 | |
| SCHEMBL2960656 | 0.73 | LMNA (0.55) | SLC8A1MAOB | |
| SCHEMBL29974296 | 0.73 | LMNA (0.55) | SLC8A1MAOB | |
| Hydrochloric Acid SCHEMBL4365431 | 0.72 | SLC8A1 (0.51) | SLC8A1 | |
| SCHEMBL8190357 | 0.70 | MAOB (0.53) | MAOBMAOAGRIN1KCNH2 | |
| SCHEMBL8190359 | 0.70 | MAOB (0.53) | MAOBMAOAGRIN1KCNH2 | |
| SCHEMBL24983614 | 0.70 | MAOB (0.39) | HTR6MAOBCA2CA5AMAOA | |
| SCHEMBL18427327 | 0.70 | MAOB (0.39) | HTR6MAOBCA2CA5AMAOA | |
| Flavane SCHEMBL14394530 | 0.69 | ESR1 (0.51) | SLC8A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700646-B2 | Compounds for use in the treatment of infection | THE UNIVERSITY OF LONDON, SCHOOL OF PHARMACY (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20070021384-A1 | Compounds for use in the treatment of infection | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021384-A1 | Compounds for use in the treatment of infection | C9, APEH, GRHPR | SLC8A1 4758/4885HTR6 2174/4885MAOB 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.