SCHEMBL353191

SCHEMBL353191

CC1(C)OB(c2cc(B3OC(C)(C)C(C)(C)O3)c3nn(-c4ccccc4-c4ccccc4)nc3c2)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 3/20 0.41
LPL P06858 2/20 0.41
PDGFRB P09619 1/20 0.35
KDR P35968 1/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
DGAT1 O75907 1/20 0.32
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352617 0.83 LPL (0.40) LIPGLPLPRMT5WDR77DGAT1
SCHEMBL17177947 0.69 LIPG (0.61) LIPGLPLPDGFRBKDRPRMT5
SCHEMBL12390740 0.67 LIPG (0.56) LIPGLPLPDGFRBKDRPRMT5
SCHEMBL12999308 0.67 LIPG (0.56) LIPGLPLPDGFRBKDRPRMT5
SCHEMBL4907823 0.67 LIPG (0.71) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL16788914 0.67 LIPG (0.62) LIPGLPLPDGFRBKDRPRMT5
SCHEMBL18544783 0.67 LIPG (0.50) LIPGLPLPDGFRBKDRPRMT5
SCHEMBL13237477 0.67 LPL (0.40) LIPGLPLPRMT5WDR77
SCHEMBL26048046 0.66 LIPG (0.61) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL18542430 0.66 LIPG (0.49) LIPGLPLPDGFRBKDRPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2409974-B1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2018-04-25 EP disclosed
US-9005776-B2 Compound having benzotriazole ring structure and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2015-04-14 US disclosed
EP-2409974-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2012-01-25 EP disclosed
US-20120012831-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT SHINSHU UNIVERSITY (JP) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012831-A1 COMPOUND HAVING BENZOTRIAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT BRD4, ARNT, MLLT1 LIPG 4699/4885LPL 4287/4885PDGFRB 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.