SCHEMBL13237477

SCHEMBL13237477

CC1(C)OB(c2ccc(-n3nc4cc(B5OC(C)(C)C(C)(C)O5)c5ccccc5c4n3)cc2)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 11/20 0.40
LIPG Q9Y5X9 11/20 0.40
ALOX5 P09917 1/20 0.38
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
P4HB P07237 1/20 0.32
HTT P42858 1/20 0.31
EGFR P00533 1/20 0.31
SNCA P37840 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13264858 0.89 ALOX5 (0.32) LPLLIPGALOX5
SCHEMBL14613133 0.89 LPL (0.34) LPLLIPGALOX5
SCHEMBL20006903 0.80 LPL (0.53) LPLLIPGP4HBHTTESR2
SCHEMBL352617 0.79 LPL (0.40) LPLLIPGPRMT5WDR77P4HB
SCHEMBL28509734 0.76 ALOX5 (0.43) LPLLIPGALOX5PRMT5WDR77
SCHEMBL28507239 0.73 LIPG (0.60) LPLLIPGP4HBHTTSNCA
SCHEMBL25548534 0.71 ALOX5 (0.40) LPLLIPGALOX5PRMT5WDR77
SCHEMBL31614465 0.69 KDM4E (0.44) LPLLIPGPRMT5WDR77P4HB
SCHEMBL10015033 0.68 LPL (0.44) LPLLIPGPRMT5WDR77P4HB
SCHEMBL12578347 0.67 MAPT (0.40) LPLLIPGHTTEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750112-B2 Polymers comprising benzotriazole for use in optical devices CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-06 US disclosed
US-20070043204-A1 Novel polymers comprising benzotriazole for use in optical devices CIBA SPECIALITY CHEMICALS CORP. 2007-02-22 US disclosed