Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3572257 | 0.98 | ESR1 (0.38) | ESR1ESR2MAOBTAAR1APLNR | |
| SCHEMBL13104799 | 0.82 | MAPT (0.42) | ESR1ESR2APLNRL3MBTL1MAPK1 | |
| SCHEMBL19464637 | 0.82 | MAPT (0.42) | ESR1ESR2APLNRL3MBTL1MAPK1 | |
| SCHEMBL13677282 | 0.82 | MAPT (0.42) | ESR1ESR2APLNRL3MBTL1MAPK1 | |
| SCHEMBL24501229 | 0.81 | ESR1 (0.42) | ESR1ESR2APLNRL3MBTL1MAPK1 | |
| SCHEMBL22808233 | 0.79 | L3MBTL1 (0.48) | ESR1ESR2APLNRL3MBTL1MAPK1 | |
| SCHEMBL17622922 | 0.78 | MAOB (0.38) | MAOBADRA2AADRA2BADRA2CPLAU | |
| SCHEMBL4337075 | 0.78 | ADRB2 (0.46) | APLNRL3MBTL1MAPK1ADRA2AADRA2B | |
| SCHEMBL4323766 | 0.78 | ADRB2 (0.46) | APLNRL3MBTL1MAPK1ADRA2AADRA2B | |
| SCHEMBL27248091 | 0.78 | ADRA2A (0.38) | ESR1ESR2MAOBAPLNRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | claimed |
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | disclosed |
| EP-2055689-A1 | Method for producing an optically active nitro compound | Sumitomo Chemical Company, Limited (JP) | 2009-05-06 | — | — | EP | disclosed |
| EP-1641740-B1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20070037976-A1 | such as 1-amino-2-phenylpropane by reacting unsaturated nitroolefin with organosilicon compounds such as poly(methylhydrosiloxane) and phenylsilane, in presence of asymmetric copper complex having phosphine ligand | SUMITOMO CHEMICAL COMPANY, LIMITED ERICK M. CARREIRA | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037976-A1 | such as 1-amino-2-phenylpropane by reacting unsaturated nitroolefin with organosilicon compounds such as poly(methylhydrosiloxane) and phenylsilane, in presence of asymmetric copper complex having phosphine ligand | L1CAM, SPATS2L, AAAS | ESR1 203/4885ESR2 355/4885MAOB 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.