SCHEMBL353322

SCHEMBL353322

COC(=O)c1ccc(Br)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.69
CA2 P00918 5/20 0.69
CA12 O43570 4/20 0.69
CA9 Q16790 4/20 0.69
CA14 Q9ULX7 4/20 0.69
CA7 P43166 3/20 0.69
XDH P47989 2/20 0.69
KDM4E B2RXH2 3/20 0.57
LMNA P02545 3/20 0.57
GAA P10253 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
POLB P06746 1/20 0.57
NFKB1 P19838 1/20 0.57
GFER P55789 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57
FUT7 Q11130 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
MAPT P10636 4/20 0.56
HPGD P15428 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550817 0.85 CA1 (0.69) CA1CA2CA12CA9CA14
SCHEMBL382159 0.85 CA1 (0.69) CA1CA2CA12CA9CA14
SCHEMBL12151586 0.84 NOTUM (0.64) CA1CA2CA12CA9CA14
SCHEMBL6507896 0.82 CA12 (0.46) CA1CA2CA12CA9CA14
Methyl Protocatechuate SCHEMBL29360855 0.82 CA1 (1.00) CA1CA2CA12CA9CA14
Methyl Protocatechuate SCHEMBL38624 0.82 CA1 (1.00) CA1CA2CA12CA9CA14
SCHEMBL15099889 0.82 CA1 (0.77) CA1CA2CA12CA9CA14
SCHEMBL205089 0.81 NOTUM (0.60) CA1CA2CA12CA9CA14
SCHEMBL851742 0.81 KDM4E (0.58) CA1CA2CA12CA9CA14
SCHEMBL2390790 0.80 CA12 (0.72) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9604929-B2 Functionalized carbon nanoparticles and functional polymer fibers prepared using the same KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-03-28 US claimed
US-20150204009-A1 FUNCTIONALIZED CARBON NANOPARTICLES AND FUNCTIONAL POLYMER FIBERS PREPARED USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-07-23 US claimed
EP-4748839-A1 POLYCYCLIC COMPOUND AND USE THEREOF CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) 2026-05-27 EP disclosed
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS LEUKOS BIOTECH S L (ES) 2026-05-21 US disclosed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
EP-4688750-A1 SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF AS AMPK ACTIVATORS Pfizer Inc. (US) 2026-02-11 EP disclosed
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-12540133-B2 Potent and selective compounds as serotonin 1B receptor modulators LEUKOS BIOTECH, S.L. (ES) 2026-02-03 US disclosed
US-20260028354-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS REGENT OF THE UNIV OF MICHIGAN (US) 2026-01-29 US disclosed
EP-4076460-B1 1,4-DIHYDRO-2H-SPIRO[ISOQUINOLINE-3,4'-PIPERIDINE DERIVATIVES AS PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-20260007681-A1 INDOLE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS UNIV MICHIGAN (US) 2026-01-08 US disclosed
WO-2004089874-A1 BIPHENYL CARBOXYLIC AMIDE P38 KINASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-10-21 WO disclosed
WO-2004041285-A1 ANTIINFLAMMATION AGENTS AMGEN INC. (US) 2004-05-21 WO disclosed
US-20040097485-A1 Antiinflammation agents TULARIK INC. 2004-05-20 US disclosed
CN-1481376-A HYDROXYBENZAMIDE DERIVATIVES AS FACTOR XA INHIBITORS ���ĵ�˹ҩ��¹����޹�˾ 2004-03-10 CN disclosed
EP-1349847-A1 OXYBENZAMIDES DERIVATIVES AS FACTOR XA INHIBITORS Aventis Pharma Deutschland GmbH (DE) 2003-10-08 EP disclosed
WO-2003068749-A1 VANILLOID RECEPTOR MODULATORS GLAXO GROUP LIMITED (GB) 2003-08-21 WO disclosed
US-20020198195-A1 New oxybenzamide derivatives useful for inhibiting factor Xa or VIIa SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2002-12-26 US disclosed
WO-2002051831-A1 OXYBENZAMIDES DERIVATIVES AS FACTOR XA INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-07-04 WO disclosed
EP-1217000-A1 Inhibitors of factor Xa and factor VIIa Aventis Pharma Deutschland GmbH (DE) 2002-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 CA1 2266/4885CA2 1909/4885CA12 2818/4885
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS HTR3B, HTR1B, HTR1A CA1 2941/4885CA2 2403/4885CA12 3845/4885
US-12540133-B2 Potent and selective compounds as serotonin 1B receptor modulators HTR3B, HTR1A, HTR1B CA1 3702/4885CA2 2854/4885CA12 4165/4885
US-20260028354-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS ESRRA, ESR2, ESRRB CA1 1445/4885CA2 1166/4885CA12 562/4885
US-20020198195-A1 New oxybenzamide derivatives useful for inhibiting factor Xa or VIIa F9, F11, F5 CA1 4325/4885CA2 2450/4885CA12 3684/4885
US-20260007681-A1 INDOLE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS ESRRA, ESR2, AR CA1 1137/4885CA2 871/4885CA12 716/4885
US-20040097485-A1 Antiinflammation agents TNF, NFATC1, NFKBIA CA1 4473/4885CA2 3538/4885CA12 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.