Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999641 | 1.00 | POLB (0.51) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11009236 | 0.89 | IAPP (0.53) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11002820 | 0.86 | MAPK1 (0.60) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9375548 | 0.86 | POLB (0.50) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL2710180 | 0.83 | MAPT (0.59) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL231627 | 0.83 | MAPT (0.59) | POLBMAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL8781834 | 0.83 | LMNA (0.55) | POLBMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL8781357 | 0.83 | VCAM1 (0.53) | POLBMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5484599 | 0.83 | LMNA (0.56) | MAPTALDH1A1SMN1; SMN2FFAR1LMNA | |
| SCHEMBL5416433 | 0.82 | POLB (0.50) | POLBMAPTMAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062440-A1 | Process for preparing phenylalkanoic acids and derivatives of benzoxazole therefrom | ELI LILLY AND COMPANY (US) | 1982-10-13 | — | — | EP | claimed |
| EP-4346810-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | Unigen, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117024371-A | Compound with function of reversing PD-1 drug resistance and application thereof | 中国人民解放军海军军医大学 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022256624-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | UNIGEN, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20220387366-A1 | Compositions for Regulating Homeostasis of Cortisol and Improving Sleep Quality and Methods of Use and Production Thereof | UNIGEN, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-10124312-B2 | Method for direct photopatterning of molecules on surfaces | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-11-13 | — | — | US | disclosed |
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
| CN-1391562-A | Quinazoline derivatives as medicaments | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | CN | disclosed |
| EP-1218354-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AstraZeneca AB (SE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2002041885-A2 | TREATMENT OF INFLAMMATION AND ASSOCIATED COMPLICATIONS USING PSEUDOHALIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-05-30 | — | — | WO | disclosed |
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001021596-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2001-03-29 | — | — | WO | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| CN-1160397-A | Azole deriv. | YAMANOUCHI PHARMA CO LTD (JP) | 1997-09-24 | — | — | CN | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0062440-A1 | Process for preparing phenylalkanoic acids and derivatives of benzoxazole therefrom | ELI LILLY AND COMPANY (US) | 1982-10-13 | — | — | EP | disclosed |