SCHEMBL3534366

SCHEMBL3534366

CC(C)(OCc1cc2nc(Cl)ccc2n1S(=O)(=O)c1cccc(Cl)c1Cl)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 18/20 0.38
SLC16A1 P53985 16/20 0.38
MCTS1 Q9ULC4 13/20 0.38
MET P08581 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3528969 0.88 PPARG (0.47) SLC16A3SLC16A1MCTS1
SCHEMBL3528148 0.86 PPARG (0.48) SLC16A3SLC16A1MCTS1
SCHEMBL3530329 0.86 MAPT (0.43) SLC16A3SLC16A1
SCHEMBL3530590 0.83 PPARG (0.39) SLC16A3SLC16A1MCTS1
SCHEMBL3530092 0.83 PPARG (0.50) SLC16A3SLC16A1MCTS1MET
SCHEMBL3532413 0.81 PPARG (0.41) SLC16A3SLC16A1MCTS1
SCHEMBL3531617 0.81 PPARG (0.48) SLC16A3SLC16A1MCTS1
SCHEMBL3533511 0.81 NOD1 (0.41) SLC16A3SLC16A1MCTS1
SCHEMBL3531699 0.81 L3MBTL1 (0.43) SLC16A3SLC16A1MCTS1
SCHEMBL3531120 0.80 PPARG (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7728002-B2 Use of pyrrolopyridine compounds for activating PPAR receptors and treatment of conditions involving such receptors LABORATOIRES FOURNIER S.A. (FR) 2010-06-01 US disclosed
US-20090239856-A1 Use of Pyrrolopyridine Compounds for Activating PPAR Receptors and Treatment of Conditions Involving Such Receptors LABORATOIRES FOURNIER S.A. (FR) 2009-09-24 US disclosed
US-7557122-B2 Pyrrolopyridine compounds, method of making them and uses thereof LABORATOIRES FOURNIER S.A. (FR) 2009-07-07 US disclosed
US-20080200495-A1 Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof LABORATOIRES FOURNIER S.A. (FR) 2008-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239856-A1 Use of Pyrrolopyridine Compounds for Activating PPAR Receptors and Treatment of Conditions Involving Such Receptors PPARD, PPARA, PPARG SLC16A3 2283/4885SLC16A1 1954/4885MCTS1 3522/4885
US-20080200495-A1 Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof LIPG, PCSK9, PNLIP SLC16A3 2244/4885SLC16A1 2383/4885MCTS1 3609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.