Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237295 | 0.86 | SIRT6 (0.68) | MAPTSIRT6L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL4772717 | 0.84 | MAPT (0.72) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL10812653 | 0.83 | LMNA (0.64) | MAPTLMNAL3MBTL1MAPK1HPGD | |
| SCHEMBL4723486 | 0.81 | L3MBTL1 (0.51) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL22652221 | 0.81 | L3MBTL1 (0.51) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL16654429 | 0.81 | GAA (0.61) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL30679043 | 0.81 | SIRT6 (0.72) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL4762192 | 0.81 | MAPT (0.57) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL28515207 | 0.80 | GAA (0.59) | MAPTSIRT6LMNAOPRM1OPRD1 | |
| SCHEMBL2927491 | 0.80 | GAA (0.55) | MAPTSIRT6LMNAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642278-B2 | Nitrogen compounds such as 3-(5-morpholin-4-yl-1H-benz-imidazol-2-yl)-1H-indazole and/or isomers, used as immunology modulators, antidiabetic agents, antiogenesis inhibitors or for prophylaxis of Alzheimer's disease | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20060079564-A1 | Indazole benzimidazole compounds | CHIRON CORPORATION | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079564-A1 | Indazole benzimidazole compounds | ABL1, ABL2, ALK | MAPT 19/4885SIRT6 4196/4885LMNA 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.