Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651872 | 0.80 | KMT2A (0.52) | L3MBTL1TSHRAOC3ALDH1A1CA2 | |
| SCHEMBL6938491 | 0.80 | TSHR (0.44) | TSHRAOC3ALDH1A1CA2CARM1 | |
| SCHEMBL28930389 | 0.79 | CA2 (0.47) | TSHRAOC3ALDH1A1CA2CARM1 | |
| SCHEMBL20549305 | 0.76 | LAP3 (0.46) | TSHRAOC3ALDH1A1CA2CA12 | |
| SCHEMBL30602696 | 0.76 | L3MBTL1 (0.38) | L3MBTL1CA2CA12CA1CA4 | |
| SCHEMBL11659162 | 0.74 | L3MBTL1 (0.43) | L3MBTL1TSHRALDH1A1CA2CA12 | |
| SCHEMBL7493141 | 0.73 | MEN1 (0.45) | L3MBTL1LMNAAOC3CA2CA12 | |
| SCHEMBL10875871 | 0.72 | AOC3 (0.54) | LMNATSHRAOC3ALDH1A1CA2 | |
| SCHEMBL14304252 | 0.71 | KCNA5 (0.56) | TSHRAOC3ALDH1A1CA2CA12 | |
| SCHEMBL8533599 | 0.71 | HPGD (0.48) | LMNATSHRALDH1A1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709479-B1 | Quinazoline derivatives and their use as pharmaceuticals | ASTRAZENECA (SE) | 2010-05-04 | — | — | US | disclosed |