Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534845 | 0.80 | L3MBTL1 (0.46) | TSHRMEN1KMT2ACA2AOC3 | |
| SCHEMBL38651872 | 0.76 | KMT2A (0.52) | TSHRMEN1KMT2ACA2AOC3 | |
| SCHEMBL28572620 | 0.76 | CA2 (0.39) | TSHRCA2ALDH1A1 | |
| SCHEMBL28930389 | 0.75 | CA2 (0.47) | TSHRCA2AOC3ALDH1A1HPGD | |
| SCHEMBL20549305 | 0.72 | LAP3 (0.46) | TSHRCA2AOC3ALDH1A1HPGD | |
| SCHEMBL3885041 | 0.70 | ALDH1A1 (0.52) | TSHRMEN1KMT2AAOC3SLC6A2 | |
| SCHEMBL10875871 | 0.68 | AOC3 (0.54) | TSHRMEN1KMT2ACA2AOC3 | |
| SCHEMBL2841914 | 0.68 | MMP2 (0.49) | TSHRMEN1KMT2ACA2MMP1 | |
| SCHEMBL14304252 | 0.67 | KCNA5 (0.56) | TSHRCA2AOC3ALDH1A1MMP1 | |
| SCHEMBL17377380 | 0.67 | L3MBTL1 (0.47) | TSHRMEN1KMT2ACA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072476-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113072476-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |
| EP-0773941-B1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6528500-B1 | Excellent antimycotic action, good aqueous solubility | SSP CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1088827-B1 | Azole derivatives or salts thereof | SSP CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6403564-B1 | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection | SCHERING CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0736030-B1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORP (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1088827-A1 | Azole derivatives or salts thereof | SSP Co., Ltd. (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5714490-A | 4-(4-(4-(-((5-(2,4-DIHALOPHENYL)--TETRAHYDRO-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)TETRAHYDROFUR-3-YL)METHOXY)PHENYL)-2,4-DIHYDRO-2-(MONO- OR DIHYDROXYALKYL)-3H-1,2,4-TRIAZOL-3-ONE; BROAD SPECTRUM; WATER SOLUBILITY; ASPERGILLUS; CANDIDA | SCHERING CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| US-5710154-A | Tetrahydrofuran antifungals | SCHERING CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5703236-A | PROTECTING; REACTING WITH GRIGNARD REAGENT; REDUCTION; CYCLIZATION; DEPROTECTING | SCHERING CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5703079-A | Tetrahydrofuran antifungals | SCHERING CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5698557-A | Hydroxy-substituted antifungals | SCHERING CORPORATION (US) | 1997-12-16 | — | — | US | disclosed |
| US-5693626-A | TREATING OR PREVENTING FUNGAL INFECTIONS BY ORAL OR PARENTERAL ADMINISTRATION | SCHERING CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5661151-A | Tetrahydrofuran antifungals | SCHERING CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0773941-A1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1997000248-A1 | HYDROXYALKYL-SUBSTITUTED TRIAZOLONES ANTIFUNGALS | SCHERING CORPORATION (US) | 1997-01-03 | — | — | WO | disclosed |
| WO-1996038443-A1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORPORATION (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0736030-A1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017407-A1 | TETRAHYDROFURAN ANTIFUNGALS | SCHERING CORPORATION (US) | 1995-06-29 | — | — | WO | disclosed |