Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 6/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381976 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1ASPHKDM8GABRP | |
| SCHEMBL12765695 | 0.78 | GABRP (0.39) | KDM4EALDH1A1MAPTGABRPGABRD | |
| SCHEMBL12183992 | 0.78 | NAPRT (0.46) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL6845540 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1CYP3A4TSHRASPH | |
| SCHEMBL19857472 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL1171022 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL1819716 | 0.75 | GABRP (0.44) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL617721 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL19857468 | 0.75 | GABRP (0.44) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL9684853 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1ALOX15MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321319-B1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-03-14 | — | — | EP | disclosed |