Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646811 | 0.85 | ABL1 (0.50) | MAPTABL1ABCB1BCRBACE1 | |
| SCHEMBL9151380 | 0.85 | ACHE (0.35) | ALDH1A1MAPTHTTABL1ABCB1 | |
| SCHEMBL28140406 | 0.83 | ABL1 (0.49) | ABL1ABCB1BCRBACE1PDE4B | |
| SCHEMBL1490970 | 0.83 | SLC6A3 (0.41) | ALDH1A1MAPTHTTNPSR1ABL1 | |
| SCHEMBL6985969 | 0.83 | SLC6A4 (0.42) | ALDH1A1MAPTHTTABL1ABCB1 | |
| SCHEMBL17514813 | 0.83 | SLC6A4 (0.42) | ABL1ABCB1BCRSQORCYP1A2 | |
| SCHEMBL16720197 | 0.83 | SMN1; SMN2 (0.38) | MAPTSQORLMNAKDM4EGAA | |
| SCHEMBL5674435 | 0.80 | ERN1 (0.38) | ALDH1A1MAPTNPSR1ABL1ABCB1 | |
| SCHEMBL9180615 | 0.80 | ACHE (0.40) | ALDH1A1ABL1HSD17B10HPGDCYP2A6 | |
| SCHEMBL8007812 | 0.80 | EGFR (0.40) | ALDH1A1MAPTMITFHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218477-B | A kind of polysubstituted benzo [b] [1,4] oxygen azatropylidene piperidine derivatives and preparation method thereof | 华侨大学 | 2017-12-01 | — | — | CN | claimed |
| EP-2029527-B1 | MODIFIED CHALCONE COMPOUNDS AS ANTIMITOTIC AGENTS | ARIZONA BIOMEDICAL RES COMMISSION (US) | 2012-08-08 | — | — | EP | claimed |
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | claimed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| US-5861402-A | BRADYKININ ANTAGONISTS USEFUL FOR THE TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, COMMON COLD, ALLERGIES, ASTHMA, PANCREATITIS, BURNS, VIRUS INFECTION, HEAD INJURY, MULTIPLE TRAUMA | PFIZER PHARMACEUTICALS, INC. (JP) | 1999-01-19 | — | — | US | claimed |
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | claimed |
| US-20210107859-A1 | A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-04-15 | — | — | US | disclosed |
| EP-3774696-A1 | A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019193068-A1 | A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2019-10-10 | — | — | WO | disclosed |
| EP-3549927-A1 | A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2019-10-09 | — | — | EP | disclosed |
| CN-105218477-B | A kind of polysubstituted benzo [b] [1,4] oxygen azatropylidene piperidine derivatives and preparation method thereof | 华侨大学 | 2017-12-01 | — | — | CN | disclosed |
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| CN-105218477-A | A kind of polysubstituted benzo [b] [Isosorbide-5-Nitrae] oxygen azatropylidene piperidine derivatives and preparation method thereof | UNIV HUAQIAO | 2016-01-06 | — | — | CN | disclosed |
| WO-2000032577-A2 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GMBH (DE) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000031039-A1 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |
| EP-0963990-A1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5939418-A | ANTICOAGULANT | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| EP-0842939-A1 | TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1998004546-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107859-A1 | A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS | OTC, MCCC2, CPS1 | ALDH1A1 407/4885MAPT 2048/4885MITF 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.