Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646811 | 0.84 | ABL1 (0.50) | RAB9ANPC1SMN1; SMN2TP53ABL1 | |
| SCHEMBL9151380 | 0.84 | ACHE (0.35) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL3535486 | 0.83 | ALDH1A1 (0.39) | RAB9ANPC1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL17514813 | 0.82 | SLC6A4 (0.42) | SLC6A3ABL1ABCB1BCRAURKB | |
| SCHEMBL6985969 | 0.82 | SLC6A4 (0.42) | SLC6A3RAB9ANPC1PTGDR2ALDH1A1 | |
| SCHEMBL28140406 | 0.82 | ABL1 (0.49) | ABL1ABCB1BCRHDAC8HSP90AA1 | |
| SCHEMBL5674435 | 0.79 | ERN1 (0.38) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL16720197 | 0.79 | SMN1; SMN2 (0.38) | RAB9ANPC1SMN1; SMN2TP53LMNA | |
| SCHEMBL19692797 | 0.78 | HRH3 (0.41) | AKT2 | |
| SCHEMBL4649572 | 0.77 | SLC6A3 (0.34) | SLC6A3RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |