Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539289 | 0.89 | KDM4E (0.61) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL646390 | 0.80 | KMT2A (0.45) | KDM4EKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1505913 | 0.79 | ALDH1A1 (0.75) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL1888780 | 0.78 | KDM4E (0.74) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL6093231 | 0.78 | KDM4E (0.77) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL3156422 | 0.77 | KDM4E (0.73) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL12204641 | 0.77 | KDM4E (0.69) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL15198807 | 0.77 | KDM4E (0.65) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL608528 | 0.76 | ALDH1A1 (0.76) | KDM4EKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6988354 | 0.76 | KDM4E (0.74) | KDM4EKMT2AALDH1A1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683070-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-7300946-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2007-11-27 | — | — | US | disclosed |
| EP-1572207-A4 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORP (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION | 2006-06-22 | — | — | US | disclosed |
| EP-1572207-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004060371-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6214845-B1 | AGRICULTURE | FMC CORPORATION | 2001-04-10 | — | — | US | disclosed |
| US-6184234-B1 | EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | KDM4E 36/4885KMT2A 614/4885ALDH1A1 1706/4885 |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | KDM4E 46/4885KMT2A 780/4885ALDH1A1 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.