Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924056 | 0.79 | NPSR1 (0.53) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL2056999 | 0.79 | NPSR1 (0.53) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL6611381 | 0.78 | NPSR1 (0.51) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL10804800 | 0.78 | NPSR1 (0.55) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL353328 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21191321 | 0.76 | ALDH1A1 (0.41) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL11558309 | 0.76 | NPC1 (0.63) | RAB9AALDH1A1NPC1HTT | |
| SCHEMBL860192 | 0.75 | L3MBTL1 (0.54) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL11919137 | 0.74 | SMYD3 (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2APOBEC3A | |
| SCHEMBL11411847 | 0.74 | TDP1 (0.49) | ALDH1A1SMN1; SMN2APOBEC3AAPOBEC3GHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
| US-4191770-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4191827-A | TRANQUILIZERS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4179566-A | TRANQUILZERS, NEUROLEPTIC AGENTS AND SLEEP INDUCERS | SANDOZ, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4170705-A | Substituted hydroxy pyridones | SANDOZ, INC. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4154928-A | Substituted isoxazolo compounds | SANDOZ, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4136114-A | INTERMEDIATES IN PREPARATION OF ALKYL AND ARYL SUBSTITUTED 4-OXO-4H-PYRAN-3-CARBOXAMIDES, ANTIALLERGENS | SANDOZ, INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4131679-A | TRANQUILIZER, MUSCLE RELAXANT | SANDOZ, INC. (US) | 1978-12-26 | — | — | US | disclosed |
| US-4124714-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS, NEUROLEPTICS, ANTIULCER AGENTS | SANDOZ, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4122182-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS, NEUROLEPTICS | SANDOZ, INC. (US) | 1978-10-24 | — | — | US | disclosed |
| US-4120967-A | TRANQUILIZERS, SLEEP INDUCERS, NEUROLEPTICS | SANDOX, INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4113727-A | Process for the preparation of substituted isoxazolo[4,5-c]pyridin-4-(5H)-ones | SANDOZ, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4064251-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-4060533-A | ANTIALLERGY | SANDOZ, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4054653-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1977-10-18 | — | — | US | disclosed |
| US-4024262-A | TRANQUILIZERS, SLEEP INDUCERS, NEUROLEPTICS | SANDOZ, INC. (US) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | RAB9A 1714/4885ALDH1A1 2806/4885NPC1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.