Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435573 | 0.78 | KDM4E (0.61) | CA12CA9CA1MAOAGAA | |
| 4-Hydroxycoumarins SCHEMBL29452306 | 0.75 | CA12 (1.00) | CA12CA9CA1MAOAGAA | |
| 4-Hydroxycoumarins SCHEMBL131312 | 0.75 | CA12 (1.00) | CA12CA9CA1MAOAGAA | |
| SCHEMBL8013758 | 0.75 | CA12 (0.46) | CA12CA9CA1MAOAKDM4E | |
| 4-Hydroxycoumarins SCHEMBL29624435 | 0.75 | CA12 (1.00) | CA12CA9CA1MAOAGAA | |
| SCHEMBL24522662 | 0.75 | CA12 (0.46) | CA12CA9CA1MAOAGAA | |
| SCHEMBL3539546 | 0.75 | PIM1 (0.64) | CA12CA9CA1HPGDMAPT | |
| 4-Hydroxycoumarins SCHEMBL30636592 | 0.73 | CA12 (0.96) | CA12CA9CA1MAOAGAA | |
| 4-Hydroxycoumarins SCHEMBL28379627 | 0.73 | CA12 (0.96) | CA12CA9CA1MAOAGAA | |
| 4-Hydroxycoumarins SCHEMBL27410815 | 0.73 | CA12 (0.96) | CA12CA9CA1MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165242-A1 | RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS | LIPHATECH INC (FR) | 2023-06-01 | — | — | US | disclosed |
| CN-113150006-B | Pyran compound and synthetic method thereof | 五邑大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113150006-A | Pyran compound and synthetic method thereof | 五邑大学 | 2021-07-23 | — | — | CN | disclosed |
| US-20210093660-A1 | COMPOSITIONS AND METHODS THAT PROMOTE HYPOXIA OR THE HYPOXIA RESPONSE FOR TREATMENT AND PREVENTION OF MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS DISORDERS | THE GENERAL HOSPITAL CORPORATION | 2021-04-01 | — | — | US | disclosed |
| US-10842812-B2 | Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190015444-A1 | COMPOSITIONS AND METHODS THAT PROMOTE HYPOXIA OR THE HYPOXIA RESPONSE FOR TREATMENT AND PREVENTION OF MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS DISORDERS | THE GENERAL HOSPITAL CORPORATION | 2019-01-17 | — | — | US | disclosed |
| EP-3334484-A2 | COMPOSITIONS AND METHODS THAT PROMOTE HYPOXIA OR THE HYPOXIA RESPONSE FOR TREATMENT AND PREVENTION OF MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS DISORDERS | The General Hospital Corporation (US) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017027810-A2 | COMPOSITIONS AND METHODS THAT PROMOTE HYPOXIA OR THE HYPOXIA RESPONSE FOR TREATMENT AND PREVENTION OF MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS DISORDERS | THE GENERAL HOSPITAL CORPORATION (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20140187625-A1 | RODENTICIDAL COMPOUND, COMPOSITION INCLUDING SAME AND USE FOR COMBATING RODENT PESTS | LIPHATECH (FR) | 2014-07-03 | — | — | US | disclosed |
| EP-2734511-A1 | RODENTICIDAL COMPOUND, COMPOSITION INCLUDING SAME AND USE FOR COMBATING RODENT PESTS | Liphatech (FR) | 2014-05-28 | — | — | EP | disclosed |
| EP-1417196-A1 | DNA-PK INHIBITORS | Cancer Research Technology Limited (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003050105-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CHEMINOVA A/S (DK) | 2003-06-19 | — | — | WO | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| US-5585357-A | Heteroaryloxymethyl ketones as interleukin-1βconverting enzyme inhibitors | SANOFI WINTHROP INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0644198-A1 | Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| CN-1069272-A | The method for preparing benzo pyrrole or thiapyran and pyrazoles | BOOTS CO PLC (GB) | 1993-02-24 | — | — | CN | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| US-4957931-A | ANTICONVULSANTS, TREATMENT OF EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| US-4859691-A | Certain 1,2-benzisoxazole derivatives | CIBA-GEIGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165242-A1 | RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS | VDR, CYP2R1, CYP24A1 | CA12 3618/4885CA9 1707/4885CA1 943/4885 |
| US-20140187625-A1 | RODENTICIDAL COMPOUND, COMPOSITION INCLUDING SAME AND USE FOR COMBATING RODENT PESTS | CASP7, CAT, CLPP | CA12 4596/4885CA9 4263/4885CA1 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.