Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | TTPA | P49638 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838222 | 0.83 | RECQL (0.38) | — | |
| SCHEMBL3537574 | 0.81 | ESR2 (0.42) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL1038871 | 0.80 | ESR2 (0.41) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL1829919 | 0.79 | ESR2 (0.38) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL16914691 | 0.79 | CA12 (0.49) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL6152189 | 0.77 | CA12 (0.47) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL17768307 | 0.77 | CA12 (0.47) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL30220183 | 0.77 | NAAA (0.48) | — | |
| SCHEMBL30220173 | 0.77 | NAAA (0.48) | — | |
| SCHEMBL3539582 | 0.77 | RECQL (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | claimed |
| EP-1778617-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NicOx S.A. (FR) | 2007-05-02 | — | — | EP | claimed |
| WO-2006008196-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NICOX S.A. (FR) | 2006-01-26 | — | — | WO | claimed |
| US-7723529-B2 | Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20100063035-A1 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES | NICOX S.A. (FR) | 2010-03-11 | — | — | US | disclosed |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | disclosed |
| EP-1778617-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NicOx S.A. (FR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006008196-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NICOX S.A. (FR) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063035-A1 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES | CA4, CA2, CA9 | PTGS2 129/4885CA12 33/4885CA1 71/4885 |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | OTUB1, TET1, TET3 | PTGS2 660/4885CA12 915/4885CA1 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.