SCHEMBL354101

SCHEMBL354101

OCCC=CCCCOCCCC=CCCO

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 2/20 0.33
LPAR3 Q9UBY5 1/20 0.33
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
MGLL Q99685 1/20 0.32
CNR2 P34972 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28734270 0.87 TSHR (0.31) TSHRLPAR3
SCHEMBL28545154 0.87 ALDH1A1 (0.52) TSHRMEN1KMT2ATHRBHTT
SCHEMBL7681089 0.83 TSHR (0.35) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL28427440 0.82 TSHR (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14355041 0.77 TSHR (0.58) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL1009437 0.76
SCHEMBL1009436 0.76
SCHEMBL316835 0.75 TSHR (0.40) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL9875583 0.75 MEN1 (0.55) TSHRMEN1KMT2ATHRBHTT
SCHEMBL316836 0.75 TSHR (0.40) TSHRMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10291918-A None JP disclosed
CN-118064224-A Fabric finishing agent and liquid detergent composition applied by same 广州立白企业集团有限公司 2024-05-24 CN disclosed
EP-3061441-B1 HAIR BLEACHING OR HAIR DYE COSMETICS KAO CORP (JP) 2020-05-20 EP disclosed
EP-3061440-B1 HAIR BLEACHING OR HAIR DYE COSMETICS KAO CORP (JP) 2020-03-11 EP disclosed
EP-2702894-B1 HAIR DECORATION ARTICLE AND HAIR DYEING AND BLEACHING METHOD USING SAME KAO CORP (JP) 2019-01-23 EP disclosed
EP-2415450-B1 AQUEOUS HAIR CLEANSING AGENT KAO CORP (JP) 2018-07-04 EP disclosed
EP-2135596-B1 HAIR COSMETIC COMPOSITIONS KAO CORP (JP) 2018-02-21 EP disclosed
US-9782340-B2 Hair bleaching or hair dye cosmetics KOA CORPORATION (JP) 2017-10-10 US disclosed
US-9782332-B2 Hair bleaching or hair dye cosmetics KAO CORPORATION (JP) 2017-10-10 US disclosed
EP-2415452-B1 AQUEOUS HAIR CLEANSING AGENT KAO CORP (JP) 2016-11-02 EP disclosed
US-20140130823-A1 HAIR DECORATION ARTICLE AND HAIR DYEING AND BLEACHING METHOD USING SAME KAO CORPORATION (JP) 2014-05-15 US disclosed
EP-2702894-A1 HAIR DECORATION ARTICLE AND HAIR DYEING AND BLEACHING METHOD USING SAME Kao Corporation (JP) 2014-03-05 EP disclosed
US-8632758-B2 Aqueous hair cleansing agent KAO CORPORATION (JP) 2014-01-21 US disclosed
EP-2415452-A1 AQUEOUS HAIR CLEANSING AGENT Kao Corporation (JP) 2012-02-08 EP disclosed
EP-2415450-A1 AQUEOUS HAIR CLEANSING AGENT Kao Corporation (JP) 2012-02-08 EP disclosed
US-20120022037-A1 AQUEOUS HAIR CLEANSING AGENT KAO CORPORATION (JP) 2012-01-26 US disclosed
US-20120015894-A1 AQUEOUS HAIR CLEANSING AGENT KAO CORPORATION (JP) 2012-01-19 US disclosed
US-20100104609-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-04-29 US disclosed
EP-2135596-A1 HAIR COSMETIC COMPOSITIIONS Kao Corporation (JP) 2009-12-23 EP disclosed
JP-H10291918-A HAIR DRESSING AGENT COMPOSITION KOSE CORP 1998-11-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104609-A1 HAIR COSMETIC COMPOSITION DSG1, CUTA, POLR1C TSHR 4039/4885MAPK1 1273/4885MEN1 155/4885
US-20120022037-A1 AQUEOUS HAIR CLEANSING AGENT POLR1C, NACA, DSG1 TSHR 4341/4885MAPK1 3591/4885MEN1 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.