Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.45 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542706 | 1.00 | ANPEP (0.47) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL200897 | 0.93 | ANPEP (0.52) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL229034 | 0.93 | ANPEP (0.52) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL200896 | 0.93 | ANPEP (0.52) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL2993124 | 0.91 | ANPEP (0.50) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL4276196 | 0.91 | ANPEP (0.50) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL2993122 | 0.91 | ANPEP (0.50) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL19928149 | 0.90 | SLC6A12 (0.42) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| Sulfuric Acid SCHEMBL4208349 | 0.85 | ANPEP (0.46) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 | |
| Sulfuric Acid SCHEMBL7803541 | 0.85 | ANPEP (0.46) | ANPEPENPEPSLC6A12SLC6A11SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | US | disclosed |
| US-7795283-B2 | Oxadiazole derivative as DGAT inhibitors | ASTRAZENECA AB (SE) | 2010-09-14 | — | — | US | disclosed |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | ASTRAZENECA AB (SE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT1, DGAT2, GPR119 | ANPEP 1442/4885ENPEP 1963/4885SLC6A12 776/4885 |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | DGAT1, DGAT2, GPR119 | ANPEP 1353/4885ENPEP 1768/4885SLC6A12 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.