SCHEMBL354414

SCHEMBL354414

Nc1ccc2[nH]c3ccccc3c(=O)c2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.67
ALDH1A1 P00352 3/20 0.67
KDM4E B2RXH2 2/20 0.67
GLA P06280 2/20 0.67
HTT P42858 2/20 0.67
LMNA P02545 1/20 0.67
HPGD P15428 1/20 0.67
ATM Q13315 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
POLB P06746 3/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
PARP1 P09874 1/20 0.64
NPC1 O15118 1/20 0.64
CASP6 P55212 1/20 0.64
ABCG2 Q9UNQ0 1/20 0.58
CTSV O60911 1/20 0.57
CTSL P07711 1/20 0.57
CDK4 P11802 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29423967 1.00 GAA (0.67) GAAALDH1A1KDM4EGLAHTT
SCHEMBL29360002 1.00 GAA (0.67) GAAALDH1A1KDM4EGLAHTT
SCHEMBL5342370 0.90 PARP1 (0.58) GAAALDH1A1KDM4EGLAHTT
SCHEMBL6325907 0.89 CDK4 (0.69) GAAALDH1A1KDM4EGLAHTT
SCHEMBL5335867 0.87 PARP1 (0.59) GAAALDH1A1KDM4EGLAHTT
SCHEMBL31473178 0.87 PARP1 (0.59) GAAALDH1A1KDM4EGLAHTT
SCHEMBL25791861 0.86 PARP1 (0.55) GAAALDH1A1KDM4EGLAHTT
Carbazole SCHEMBL28862120 0.84 PARP1 (0.67) GAAALDH1A1KDM4EGLAHTT
SCHEMBL29565567 0.84 PARP1 (0.67) GAAALDH1A1KDM4EGLAHTT
SCHEMBL29483487 0.84 PARP1 (0.67) GAAALDH1A1KDM4EGLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015033743-A1 METHOD FOR PREPARING LABELED SUGAR CHAIN SAMPLE 住友ベークライト株式会社 (JP) 2015-03-12 WO claimed
US-8828732-B2 Method of labeling sugar chain SUMITOMO BAKELITE CO., LTD. (JP) 2014-09-09 US claimed
EP-2685263-A1 SUGAR CHAIN FLUORESCENT LABELING METHOD Sumitomo Bakelite Co., Ltd. (JP) 2014-01-15 EP claimed
EP-2282209-B1 METHOD FOR LABELLING SUGAR CHAINS SUMITOMO BAKELITE CO (JP) 2012-10-03 EP claimed
US-20110089033-A1 METHOD OF PREPARING SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD OF ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-04-21 US claimed
EP-2295962-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN Sumitomo Bakelite Co., Ltd. (JP) 2011-03-16 EP claimed
US-20110046364-A1 METHOD OF LABELING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-02-24 US claimed
EP-2282209-A1 METHOD FOR LABELLING SUGAR CHAINS Sumitomo Bakelite Company Limited (JP) 2011-02-09 EP claimed
WO-2009150834-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN 住友ベークライト株式会社 (JP) 2009-12-17 WO claimed
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2026-02-10 US disclosed
EP-4473051-B1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PREPARING THE COMPOUND, AND USE OF THE COMPOUND AS AN ANTI-AGING AGENT AND/OR ANTIOXIDANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-11-12 EP disclosed
EP-3896074-B1 METHOD, KIT, AND DEVICE FOR PREPARING GLYCAN FROM GLYCOPROTEIN AIST (JP) 2023-10-25 EP disclosed
WO-2023164238-A1 PROTEASE INHIBITORS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2023-08-31 WO disclosed
WO-2023143677-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PREPARING THE COMPOUND, AND USE OF THE COMPOUND AS AN ANTI-AGING AGENT AND/OR ANTIOXIDANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2023-08-03 WO disclosed
US-20050070568-A1 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2005-03-31 US disclosed
EP-1474397-A1 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS Cancer Research Technology Limited (GB) 2004-11-10 EP disclosed
US-20040191792-A1 Acridone derivatives as labels for fluorescence detection of target materials GE HEALTHCARE UK LIMITED (GB) 2004-09-30 US disclosed
EP-1392776-A2 ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS Amersham Biosciences UK Limited (GB) 2004-03-03 EP disclosed
WO-2003059885-A1 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2003-07-24 WO disclosed
WO-2002099424-A2 ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS AMERSHAM BIOSCIENCES UK LIMITED (GB) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070568-A1 Therapeutic acridone and acridine compounds CCNK, TERT, CCNA1 GAA 3128/4885ALDH1A1 99/4885KDM4E 884/4885
US-20110046364-A1 METHOD OF LABELING SUGAR CHAIN SLC2A2, FUT6, SLC2A1 GAA 60/4885ALDH1A1 840/4885KDM4E 2891/4885
US-20040191792-A1 Acridone derivatives as labels for fluorescence detection of target materials ACR, ARSA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 GAA 2987/4885ALDH1A1 1640/4885KDM4E 3007/4885
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein FUT7, FUT4, SIGLEC7 GAA 113/4885ALDH1A1 1573/4885KDM4E 1909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.