Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 19/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 19/20 | 0.45 |
| ▸ | GABRP | O00591 | 18/20 | 0.45 |
| ▸ | GABRD | O14764 | 18/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 18/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 18/20 | 0.45 |
| ▸ | GABRE | P78334 | 18/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444716 | 0.79 | GABRA2 (0.52) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL8822906 | 0.78 | GABRA2 (0.38) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL3539387 | 0.76 | GABRA2 (0.49) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL3544361 | 0.74 | GABRA2 (0.47) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL922220 | 0.74 | GABRP (0.62) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL8822734 | 0.72 | GABRA2 (0.41) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL15218269 | 0.71 | GABRP (0.55) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL8822814 | 0.70 | GABRA2 (0.38) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL18393352 | 0.69 | GABRA2 (0.51) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6055756 | 0.69 | GABRA2 (0.51) | GABRA2GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765774-B1 | PESTICIDAL AGENTS ON THE BASIS OF 1-ARYL-AMINOPYRROL | MERIAL LTD (US) | 2012-10-24 | — | — | EP | disclosed |
| US-7674474-B2 | Pesticidal agents on the basis of 1-aryl-aminopyrrol | MERIAL LIMITED (US) | 2010-03-09 | — | — | US | disclosed |
| US-20070281976-A1 | PESTICIDAL AGENTS ON THE BASIS OF 1-ARYL-AMINOPYRROL | MERIAL, INC. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281976-A1 | PESTICIDAL AGENTS ON THE BASIS OF 1-ARYL-AMINOPYRROL | DDT, DDC, ACHE | GABRA2 1047/4885GABRB2 1657/4885GABRP 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.