⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27751277 | 0.78 | NOS3 (0.44) | — | |
| SCHEMBL5250431 | 0.78 | MKNK1 (0.57) | — | |
| SCHEMBL8557630 | 0.77 | — | — | |
| SCHEMBL9764414 | 0.77 | — | — | |
| SCHEMBL4322611 | 0.77 | GABRP (0.50) | — | |
| SCHEMBL730405 | 0.76 | CCR1 (0.42) | — | |
| SCHEMBL29387096 | 0.76 | CCR1 (0.42) | — | |
| SCHEMBL30259554 | 0.74 | CCR1 (0.41) | — | |
| SCHEMBL986987 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL30259309 | 0.74 | CCR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028086-B2 | Pyrido-imidazo rifamycins | BIOFER S.P.A. (IT) | 2021-06-08 | — | — | US | claimed |
| EP-3645539-B1 | PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT | BIOFER SPA (IT) | 2021-04-07 | — | — | EP | claimed |
| US-20200157104-A1 | PYRIDO-IMIDAZO RIFAMYCINS | BIOFER S.P.A. (IT) | 2020-05-21 | — | — | US | claimed |
| EP-3645539-A1 | PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT | Biofer S.p.A. (IT) | 2020-05-06 | — | — | EP | claimed |
| CN-110770244-A | Antibacterial agent of pyridoimidazole rifamycin derivative | 倍尔福股份公司 | 2020-02-07 | — | — | CN | claimed |
| WO-2019003076-A1 | PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT | BIOFER S.P.A. (IT) | 2019-01-03 | — | — | WO | claimed |
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20210363143-A1 | PYRIDO-IMIDAZO RIFAMYCINS | BIOFER S.P.A. (IT) | 2021-11-25 | — | — | US | disclosed |
| US-20210340105-A1 | AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF | Cortexyme, Inc. (US) | 2021-11-04 | — | — | US | disclosed |
| US-11059786-B2 | Aminopyridine compounds and methods for the preparation and use thereof | Cortexyme, Inc. (US) | 2021-07-13 | — | — | US | disclosed |
| WO-2021116446-A1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-06-17 | — | — | WO | disclosed |
| US-11028086-B2 | Pyrido-imidazo rifamycins | BIOFER S.P.A. (IT) | 2021-06-08 | — | — | US | disclosed |
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-7056917-B2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20060106034-A1 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-18 | — | — | US | disclosed |
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | TRINE PHARMACEUTICALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1389463-A1 | MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-20030092720-A1 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2003-05-15 | — | — | US | disclosed |